The diagnostic value of lymph node biopsy to detect Castleman’s disease

dc.contributor.authorSoma, Prashilla
dc.contributor.authorKara, S.
dc.contributor.emailprashilla.soma@up.ac.zaen_US
dc.date.accessioned2014-10-08T05:42:46Z
dc.date.available2014-10-08T05:42:46Z
dc.date.issued2014-09
dc.description.abstractHIV is not indicated in the aetiology of Castleman’s disease. However, it impacts on the prevalence and natural history of this disease and signi cantly on the disease progression. Castleman’s disease is a uni- or multicentric disease of the lymph node with or without polyclonal proliferation of B-cells. It is a morphologically distinct form of lymph node hyperplasia and is characterised by signi cant architectural changes in all lymphatic compartments. Histopathologically, the disease is classi ed into two major subtypes: the hyaline-vascular type and the plasma-cell type. A mixed type is also identi ed, as there are frequent transitions between the types. e diagnosis of Castleman’s disease needs to be made histologically. Treatment modalities include surgery, which is curative for unicentric disease, and systemic therapy, which is needed for multicentric disease. is case highlights the diagnostic value of lymph node excision biopsy in HIV-infected patients.en_US
dc.description.librarianam2014en_US
dc.description.urihttp://www.sajhivmed.org.zaen_US
dc.identifier.citationSoma, P & Kara, S 2014, 'The diagnostic value of lymph node biopsy to detect Castleman’s disease', Southern African Journal of HIV Medicine, vol. 15, no. 3, pp. 110-111.en_US
dc.identifier.issn1608-9693 (print)
dc.identifier.issn2078-6751 (online)
dc.identifier.other10.7196/SAJHIVMED.1065
dc.identifier.urihttp://hdl.handle.net/2263/42280
dc.language.isoenen_US
dc.publisherHealth and Medical Publishing Groupen_US
dc.rightsHealth and Medical Publishing Groupen_US
dc.subjectCastleman’s diseaseen_US
dc.subjectHuman immunodeficiency virus (HIV)en_US
dc.subjectLymph node biopsyen_US
dc.titleThe diagnostic value of lymph node biopsy to detect Castleman’s diseaseen_US
dc.typeArticleen_US

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