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Application of reactor engineering concepts in continuous flow chemistry : a review

dc.contributor.authorNeyt, Nicole Candice
dc.contributor.authorRiley, Darren Lyall
dc.contributor.emaildarren.riley@up.ac.zaen_US
dc.date.accessioned2022-07-28T06:53:05Z
dc.date.available2022-07-28T06:53:05Z
dc.date.issued2021-08
dc.description.abstractThe adoption of flow technology for the manufacture of chemical entities, and in particular pharmaceuticals, has seen rapid growth over the past two decades with the technology now blurring the lines between chemistry and chemical engineering. Current indications point to a future in which flow chemistry and related technologies will be a major player in modern chemical manufacturing and the 4th industrial revolution. In this review we highlight the application of new reactor configurations and designs in the context of either bespoke or commercial flow apparatus specifically related to microwave chemistry, photochemical transformations, electrochemical promoted reactions and multi-phasic reactions. In addition, we look at how 3D printing in reactor design and computer-aided automation is growing within the field and finally describe how innovative solutions are being developed to tackle challenging downstream processing operations.en_US
dc.description.departmentChemistryen_US
dc.description.sponsorshipNational Research Foundation, and Pelchem Pty Ltd.en_US
dc.description.urihttp://www.rsc.org/journals-books-databases/about-journals/reaction-chemistry-engineeringen_US
dc.identifier.citationNeyt, Nicole & Riley, Darren. (2021). Application of reactor engineering concepts in continuous flow chemistry: a review. Reaction Chemistry & Engineering. 6(8): 1295-1326, doi: 10.1039/D1RE00004G.en_US
dc.identifier.issn2058-9883 (online)
dc.identifier.other10.1039/d1re00004g
dc.identifier.urihttps://repository.up.ac.za/handle/2263/86521
dc.language.isoenen_US
dc.publisherRoyal Society of Chemistryen_US
dc.rightsThis journal is © The Royal Society of Chemistry 2021.en_US
dc.subjectFlow technologyen_US
dc.subjectChemistryen_US
dc.subjectFlow chemistryen_US
dc.subjectChemical manufacturingen_US
dc.subjectChemical engineeringen_US
dc.subjectCommercial flow apparatusen_US
dc.subjectMicrowave chemistryen_US
dc.subjectPhotochemical transformationen_US
dc.subjectMulti-phasic reactionsen_US
dc.subjectElectrochemical promoted reactionsen_US
dc.titleApplication of reactor engineering concepts in continuous flow chemistry : a reviewen_US
dc.typeArticleen_US

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