Lung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africa

dc.contributor.advisorEhlers, M.M. (Marthie Magdaleen)
dc.contributor.coadvisorGoga, Ameena Ebrahim
dc.contributor.emailrashmikanaidoo@gmail.comen_US
dc.contributor.postgraduateNaidoo, Rashmika
dc.date.accessioned2022-08-02T09:14:34Z
dc.date.available2022-08-02T09:14:34Z
dc.date.created2022-09-09
dc.date.issued2022
dc.descriptionThesis (PhD (Medical Microbiology))--University of Pretoria, 2022.en_US
dc.description.abstractBronchiectasis is a heterogeneous disease with multiple aetiologies and diverse clinical phenotypes. The pathogenesis of bronchiectasis, a growing economic health burden, is poorly understood. While culture-independent technologies have significantly increased the understanding of the lung microbiome, there is limited data on the lung microbiome, resistome and virome from bronchiectasis patients with and without HIV on the African continent. Therefore, the purpose of this study was to identify the lung microbiome, resistome and virome in bronchiectasis patients in Pretoria, South Africa, in order to determine whether HIV status affects the bacterial and viral lung composition and accompanying antimicrobial resistance (AMR) observed.en_US
dc.description.availabilityUnrestricteden_US
dc.description.degreePhD (Medical Microbiology)en_US
dc.description.departmentMedical Microbiologyen_US
dc.description.sponsorshipNational Research Foundation University of Pretoriaen_US
dc.identifier.citation*en_US
dc.identifier.doihttps://doi.org/10.25403/UPresearchdata.20411547en_US
dc.identifier.otherS2022
dc.identifier.urihttps://repository.up.ac.za/handle/2263/86643
dc.language.isoenen_US
dc.publisherUniversity of Pretoria
dc.rights© 2022 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
dc.subjectBronchiectasisen_US
dc.subjectHeterogeneous diseaseen_US
dc.subjectPathogenesisen_US
dc.subjectLung microbiomeen_US
dc.subjectResistomeen_US
dc.subjectViromeen_US
dc.subjectHIV virusen_US
dc.subjectSouth Africaen_US
dc.subjectUCTD
dc.titleLung microbiome and antimicrobial resistome of bronchiectasis patients attending a clinic at a tertiary academic hospital in Pretoria, South Africaen_US
dc.typeThesisen_US

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