Virulence of Brucella abortus isolated from cattle and water buffalo

dc.contributor.authorAdesiyun, Abiodun Adewale
dc.contributor.authorFosgate, Geoffrey Theodore
dc.contributor.authorSeebaransingh, Ravi
dc.contributor.authorBrown, Gabriel
dc.contributor.authorStoute, Simone
dc.contributor.authorStewart-Johnson, Alva
dc.contributor.emailgeoffrey.fosgate@up.ac.zaen
dc.date.accessioned2011-03-04T10:39:17Z
dc.date.available2011-03-04T10:39:17Z
dc.date.issued2011-01
dc.description.abstractBrucellosis has been documented in domestic water buffalo (Bubalus bubalis) but published literature is limited despite the importance of this species in tropical agricultural systems. The objective of this study was to compare the virulence of Brucella abortus isolates recovered from cattle and water buffalo. Nineteen strains of B. abortus from cattle and domestic water buffalo in Trinidad were intraperitoneally inoculated into BALB/c mice. Spleens were cultured for B. abortus and histopathological severity scores were calculated based on lymphoid depletion, lymphoid necrosis, splenitis, and macrophage accumulation. A general linear model approach was used to estimate the effect of isolate source (cattle versus water buffalo) on virulence. Isolates of water buffalo origin were significantly less virulent in the mouse model based on recovered B. abortus from splenic tissues, spleen/weight ratio, and lymphoid necrosis but not overall histopathological severity scores. Further investigation of isolates recovered from water buffalo might provide the key to the development of procedures for brucellosis control in tropical environments.en
dc.description.sponsorshipThe authors are grateful to the Campus Research Funds Committee, St. Augustine Campus for funding the research project.en
dc.identifier.citationAdesiyun, AA, Fosgate, GT, Seebaransingh, R, Brown, G, Stoute, S & Stewart-Johnson, A 2011, 'Virulence of Brucella abortus isolated from cattle and water buffalo', Tropical Animal Health and Production, vol. 43, no. 1, pp. 13-16, doi: 10.1007/s11250-010-9679-y. [http://www.springerlink.com/content/0049-4747]en
dc.identifier.issn0049-4747
dc.identifier.issn1573-7438 (online)
dc.identifier.other10.1007/s11250-010-9679-y.
dc.identifier.other6603440077
dc.identifier.urihttp://hdl.handle.net/2263/15966
dc.language.isoenen
dc.publisherSpringeren
dc.relation.requiresAdobe Acrobat Readeren
dc.rights© Springer Science+Business Media B.V. 2010. The original publication is available at www.springerlink.comen
dc.subjectBrucellosisen
dc.subjectCattleen
dc.subjectTrinidaden
dc.subjectWater buffalo (Bubalus bubalis)en
dc.subjectVirulenceen
dc.subject.lcshCattle -- Diseasesen
dc.subject.lcshBrucella abortusen
dc.subject.lcshBrucellosis in cattleen
dc.subject.lcshCattle -- Infectionsen
dc.subject.lcshBrucellosis in animalsen
dc.titleVirulence of Brucella abortus isolated from cattle and water buffaloen
dc.typePostprint Articleen

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