The effect of sympathomimetic medication on cardiovascular functioning of children with attention-deficit / hyperactivity disorder

dc.contributor.authorNegrao, Bianca Lee
dc.contributor.authorCrafford, Dalene
dc.contributor.authorViljoen, Margaretha
dc.contributor.emailmviljoen@medic.up.ac.zaen_US
dc.date.accessioned2009-11-18T07:02:59Z
dc.date.available2009-11-18T07:02:59Z
dc.date.issued2009-09
dc.description.abstractOBJECTIVE : The aim of this study was to investigate the effects of sympathomimetic medication on the cardiovascular system of children with attention-deficit / hyperactivity disorder (ADHD). METHODS : Cardiovascular functioning of children with ADHD (n = 19) was tested while the children were stimulant free and during a period in which they were on stimulant medication. Electrocardiograms (ECGs) were obtained by means of a Schiller CardioLaptop AT-110 ECG recorder using the standard 12-lead cable positioning for a resting ECG. Blood pressure was measured by means of a stethoscope and mercury sphygmomanometer. RESULTS : The main findings of this study were that methylphenidate usage is associated with increases in heart rate (HR) and blood pressure (BP), and that it does not adversely affect HR-corrected QT and JT intervals or cardiac dispersion values. CONCLUSION : Methylphenidate causes an increase in HR as well as increases in both systolic and diastolic BP, but no change in cardiac depolarisation and repolarisation duration or homogeneity.en_US
dc.identifier.citationNegrao, BL, Crafford, D & Viljoen, M 2009, 'The effect of sympathomimetic medication on cardiovascular functioning of children with attention-deficit / hyperactivity disorder', Cardiovascular Journal of Africa, vol. 20, no. 5, pp. 296-299. [http://www.cvjsa.co.za]en_US
dc.identifier.issn1015-9657
dc.identifier.urihttp://hdl.handle.net/2263/11886
dc.language.isoenen_US
dc.publisherClinics Cardiven_US
dc.rightsClinics Cardiven_US
dc.subject.lcshSympathomimetic agentsen
dc.subject.lcshAttention deficit hyperactivity disorder (ADHD)en
dc.subject.lcshMethylphenidateen
dc.subject.lcshCardiovascular pharmacologyen
dc.titleThe effect of sympathomimetic medication on cardiovascular functioning of children with attention-deficit / hyperactivity disorderen_US
dc.typeArticleen_US

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