The effect of sympathomimetic medication on cardiovascular functioning of children with attention-deficit / hyperactivity disorder
dc.contributor.author | Negrao, Bianca Lee | |
dc.contributor.author | Crafford, Dalene | |
dc.contributor.author | Viljoen, Margaretha | |
dc.contributor.email | mviljoen@medic.up.ac.za | en_US |
dc.date.accessioned | 2009-11-18T07:02:59Z | |
dc.date.available | 2009-11-18T07:02:59Z | |
dc.date.issued | 2009-09 | |
dc.description.abstract | OBJECTIVE : The aim of this study was to investigate the effects of sympathomimetic medication on the cardiovascular system of children with attention-deficit / hyperactivity disorder (ADHD). METHODS : Cardiovascular functioning of children with ADHD (n = 19) was tested while the children were stimulant free and during a period in which they were on stimulant medication. Electrocardiograms (ECGs) were obtained by means of a Schiller CardioLaptop AT-110 ECG recorder using the standard 12-lead cable positioning for a resting ECG. Blood pressure was measured by means of a stethoscope and mercury sphygmomanometer. RESULTS : The main findings of this study were that methylphenidate usage is associated with increases in heart rate (HR) and blood pressure (BP), and that it does not adversely affect HR-corrected QT and JT intervals or cardiac dispersion values. CONCLUSION : Methylphenidate causes an increase in HR as well as increases in both systolic and diastolic BP, but no change in cardiac depolarisation and repolarisation duration or homogeneity. | en_US |
dc.identifier.citation | Negrao, BL, Crafford, D & Viljoen, M 2009, 'The effect of sympathomimetic medication on cardiovascular functioning of children with attention-deficit / hyperactivity disorder', Cardiovascular Journal of Africa, vol. 20, no. 5, pp. 296-299. [http://www.cvjsa.co.za] | en_US |
dc.identifier.issn | 1015-9657 | |
dc.identifier.uri | http://hdl.handle.net/2263/11886 | |
dc.language.iso | en | en_US |
dc.publisher | Clinics Cardiv | en_US |
dc.rights | Clinics Cardiv | en_US |
dc.subject.lcsh | Sympathomimetic agents | en |
dc.subject.lcsh | Attention deficit hyperactivity disorder (ADHD) | en |
dc.subject.lcsh | Methylphenidate | en |
dc.subject.lcsh | Cardiovascular pharmacology | en |
dc.title | The effect of sympathomimetic medication on cardiovascular functioning of children with attention-deficit / hyperactivity disorder | en_US |
dc.type | Article | en_US |