Prevalence of peripheral vestibular impairment in adults with human immunodeficiency virus

dc.contributor.authorMillar, Alison
dc.contributor.authorJoubert, Karin
dc.contributor.authorNaudé, Alida Maryna
dc.date.accessioned2021-06-07T10:29:28Z
dc.date.available2021-06-07T10:29:28Z
dc.date.issued2021
dc.description.abstractBACKGROUND AND OBJECTIVES : Globally, the human immunodeficiency virus (HIV) is responsible for one of the most serious pandemics to date. The vulnerability of the vestibular system in individuals with HIV has been confirmed, and central vestibular impairments have been frequently reported. However, there are disagreements on the impact of HIV on peripheral vestibular function. Thus, the current study aimed to determine the prevalence of peripheral vestibular impairment, specifically related to the semi-circular canals (SCCs), in HIV-positive individuals receiving antiretroviral (ARV) treatment. SUBJECTS AND METHODS : A total of 92 adults between the ages of 18 and 50 years (divided into two groups) participated in the study. The first group comprised HIV-positive individuals receiving ARV treatment (n1=60), and the second group comprised HIV-negative participants (n2=32). The video head impulse test was used to conduct the head impulse paradigm (HIMP). RESULTS : Bilateral normal HIMP results were obtained in 95% of the HIV-positive participants and all HIV-negative participants. The gain of the left posterior SCCs was significantly lower in the HIV-positive group, while the gains of all other canals between the two groups were comparable. CONCLUSIONS : The prevalence of peripheral vestibular impairment in the HIV-positive group was not significantly different from that of the HIV-negative group. The reduced prevalence in the current study may be attributed to participant characteristics, the test battery employed, and the central compensation of the vestibular dysfunctions at the later stages of infection.en_ZA
dc.description.departmentCentre for Augmentative and Alternative Communication (CAAC)en_ZA
dc.description.librarianam2021en_ZA
dc.description.urihttps://www.ejao.orgen_ZA
dc.identifier.citationMillar, A., Joubert, K. & Naude, A. 2020, 'Prevalence of peripheral vestibular impairment in adults with human immunodeficiency virus', Journal of Audiology and Otology, vol. 25, no. 1, pp. 36-42.en_ZA
dc.identifier.issn2384-1621 (print)
dc.identifier.issn2384-1710 (online)
dc.identifier.other10.7874/jao.2020.00164
dc.identifier.urihttp://hdl.handle.net/2263/80235
dc.language.isoenen_ZA
dc.publisherKorean Audiological Society and Korean Otological Societyen_ZA
dc.rights© 2021 The Korean Audiological Society and Korean Otological Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License.en_ZA
dc.subjectVestibular diseasesen_ZA
dc.subjectHead impulse testen_ZA
dc.subjectVestibular function testsen_ZA
dc.subjectHuman immunodeficiency virus (HIV)en_ZA
dc.subjectPeripheral vestibular impairmenten_ZA
dc.subjectSemi-circular canals (SCCs)en_ZA
dc.subjectAntiretroviral (ARV)en_ZA
dc.subjectHead impulse paradigm (HIMP)en_ZA
dc.titlePrevalence of peripheral vestibular impairment in adults with human immunodeficiency virusen_ZA
dc.typeArticleen_ZA

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