Aetiology of Jaagsiekte : transmission by means of subcellular fractions and evidence for the involvement of a retrovirus

dc.contributor.authorVerwoerd, Daniel Wynand
dc.contributor.authorDe Villiers, Ethel-Michele
dc.contributor.authorTustin, R.C.
dc.contributor.editorBigalke, R.D.
dc.contributor.editorCameron, Colin McKenzie
dc.contributor.editorGilchrist, Frances M.C.
dc.contributor.editorMorren, A.J.
dc.contributor.editorVerster, Anna J.M.
dc.contributor.editorVerwoerd, Daniel Wynand
dc.contributor.editorWalker, Jane B.
dc.contributor.otherSteyn, P.J.J.
dc.date.accessioned2016-07-07T09:40:10Z
dc.date.available2016-07-07T09:40:10Z
dc.date.created2016
dc.date.issued1980
dc.descriptionThe articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.en_ZA
dc.description.abstractJaagsiekte (ovine pulmonary adenomatosis) was transmitted to new-born lambs by inoculation of the microsomal fraction of a cytoplasmic extract of cultured tumour cells or tumour tissue. Various treatments of the biologically active fraction were carried out to differentiate between various classes of possible aetiological agents. The results obtained suggested the involvement of a membraneassociated RNA containing virus. Reverse transcriptase activity dependent on Mg++ was subsequently demonstrated in these extracts and in lung exudate, and was shown to be associated with particles banding at a density of 1 , 175 in sucrose gradients. These characteristics, as well as the appearance of the particles in the electron microscope, are similar to those reported for Type B and Type D retroviruses. Serial transmissions of jaagsiekte over a number of years, using cytoplasmic extracts and purified virus, strongly suggest that this virus is the aetiologic agent of jaagsiekte.en_ZA
dc.identifier.citationVerwoerd, DW, Williamson, A-L, & Tustin, RC, E-M 1980, 'Aetiology of Jaagsiekte : transmission by means of subcellular fractions and evidence for the involvement of a retrovirus’, Onderstepoort Journal of Veterinary Research, vol. 47, no. 4, pp. 275-280.en_ZA
dc.identifier.issn0330-2465
dc.identifier.urihttp://hdl.handle.net/2263/54218
dc.language.isoenen_ZA
dc.publisherPretoria : The Government Printeren_ZA
dc.rights©1980 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©2016 University of Pretoria Department of Library Services (digital).en_ZA
dc.subjectJaagsiekteaf_ZA
dc.subject.lcshVeterinary medicine -- South Africa
dc.titleAetiology of Jaagsiekte : transmission by means of subcellular fractions and evidence for the involvement of a retrovirusen_ZA
dc.typeArticleen_ZA

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