Assessment of a portable lactate meter for field use in the white rhinoceros (Ceratotherium simum)

dc.contributor.authorCole, Georgina C.
dc.contributor.authorTordiffe, Adrian Stephen Wolferstan
dc.contributor.authorSteenkamp, Gerhardus
dc.date.accessioned2018-03-12T06:48:51Z
dc.date.available2018-03-12T06:48:51Z
dc.date.issued2017-11-10
dc.description.abstractBlood lactate is a predictor of mortality in critically ill humans and animals. Handheld lactate meters have the potential to be used in the field to evaluate the condition of severely injured rhinoceroses but have not been compared with laboratory-based methods. Agreement between a handheld lactate meter and a laboratory method was assessed, as was the stability of rhino blood lactate in the anticoagulant sodium fluoride/potassium oxalate (fluoride/oxalate). Blood samples were obtained from 53 white rhinos that had been immobilised for management reasons. Lactate was measured by means of a handheld meter using whole blood in heparin (WBHEP), whole blood in fluoride/oxalate (WBFO) and fluoride/oxalate plasma (PFO). Results were recorded in both blood (BL) and plasma (PL) modes and compared to an established laboratory method for measuring plasma lactate. To assess the stability of lactate over time, blood lactate in fluoride/oxalate was measured on the handheld meter at intervals for up to 91 h. Agreement was best using WBFO in PL mode, with small bias (-0.16), tight 95% limits of agreement (LOA) (-1.46, 1.14) and a Pc (95% CI) of 0.97 (0.92, 0.99). The agreement was improved for all sample types when using the PL mode compared to the blood lactate (BL) mode. Blood lactate was stable in fluoride/oxalate for 91 h, with a mean change from baseline of 0.15 (-0.178, 0.478) mmol/L (mean, 95% CI). The handheld meter was found to be suitable for field use in white rhinos but provided more reliable results with the device in PL mode. Furthermore, rhino blood lactate was found to be stable in fluoride/oxalate for as long as 3 days.en_ZA
dc.description.departmentCompanion Animal Clinical Studiesen_ZA
dc.description.departmentParaclinical Sciencesen_ZA
dc.description.librarianam2018en_ZA
dc.description.sponsorshipThe Zebra Foundation of the British Veterinary Zoological Societyen_ZA
dc.description.urihttp://www.ojvr.orgen_ZA
dc.identifier.citationCole, G.C., Tordiffe, A.S.W. & Steenkamp, G., 2017, ‘Assessment of a portable lactate meter for field use in the white rhinoceros (Ceratotherium simum)’, Onderstepoort Journal of Veterinary Research 84(1), a1399. https://DOI.org/ 10.4102/ojvr.v84i1.1399.en_ZA
dc.identifier.issn2219-0635 (print)
dc.identifier.issn0030-2465 (online)
dc.identifier.issn10.4102/ojvr.v84i1.1399
dc.identifier.urihttp://hdl.handle.net/2263/64188
dc.language.isoenen_ZA
dc.publisherAOSIS OpenJournalsen_ZA
dc.rights© 2017. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.en_ZA
dc.subjectLaboratory methoden_ZA
dc.subjectMortalityen_ZA
dc.subjectWhole blood in heparin (WBHEP)en_ZA
dc.subjectWhole blood in fluoride/oxalate (WBFO)en_ZA
dc.subjectFluoride/oxalate plasma (PFO)en_ZA
dc.subjectBlood (BL)en_ZA
dc.subjectPlasma (PL)en_ZA
dc.subjectPortable lactate meteren_ZA
dc.subjectWhite rhinoceros (Ceratotherium simum)en_ZA
dc.titleAssessment of a portable lactate meter for field use in the white rhinoceros (Ceratotherium simum)en_ZA
dc.typeArticleen_ZA

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