Practical considerations when interpreting FDG PET/CT imaging for staging and treatment response assessment in melanoma patients

dc.contributor.authorVan de Wiele, Christophe
dc.contributor.authorJuanito, Gebreurs
dc.contributor.authorVander, Borght K.
dc.contributor.authorLawal, Ismaheel Opeyemi
dc.contributor.authorSathekge, Mike Machaba
dc.contributor.authorMaes, Alex
dc.contributor.authorDe Spiegeleer, Bart
dc.date.accessioned2022-09-09T10:28:22Z
dc.date.issued2021-11
dc.description.abstractWhile FDG PET/CT bears a high sensitivity and specificity for the staging of stage III and IV melanoma as well as for the purpose of melanoma recurrence detection, overall results tend to vary from one part of the body to another as well as for melanoma from cutaneous or choroidal origin. In this paper, organ or site-related differences in sensitivity and specificity in melanoma patients, both from cutaneous and choroidal origin, as well as their impact on clinical decision making are discussed. Furthermore, with the advent of immunotherapy for the treatment of malignant melanoma, post-treatment related potential false positive findings have emerged, the knowledge of which is essential for accurate treatment response assessment. These post-treatment related potential false positive findings are summarized in this paper so as to help the nuclear medicine physician in avoiding erroneous interpretation of acquired FDG PET/CT images in melanoma patients receiving immuntherapy.en_US
dc.description.departmentNuclear Medicineen_US
dc.description.embargo2022-10-01
dc.description.librarianhj2022en_US
dc.description.urihttps://www.seminarsinnuclearmedicine.comen_US
dc.identifier.citationVan de Wiele, C., Juanito, G., Vander, B.K. et al. 2021, 'Practical considerations when interpreting FDG PET/CT imaging for staging and treatment response assessment in melanoma patients', Seminars in Nuclear Medicine, vol. 51, no. 6, pp. 544-553, doi : 10.1053/j.semnuclmed.2021.06.010.en_US
dc.identifier.issn0001-2998 (print)
dc.identifier.issn1558-4623 (online)
dc.identifier.other10.1053/j.semnuclmed.2021.06.010
dc.identifier.urihttps://repository.up.ac.za/handle/2263/87137
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rights© 2021 Elsevier Inc. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Seminars in Nuclear Medicine. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Seminars in Nuclear Medicine, vol. 51, no. 6, pp. 544-553, 2021. doi : 10.1053/j.semnuclmed.2021.06.010.en_US
dc.subjectFluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT)en_US
dc.titlePractical considerations when interpreting FDG PET/CT imaging for staging and treatment response assessment in melanoma patientsen_US
dc.typePostprint Articleen_US

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