Therapeutic switching of metformin using heteroleptic Cu(II) and Zn(II) complexes : a combined experimental and computational study

Alem, Mamaru B.; Koobotse, Moses O.; Demissie, Taye B.; Desalegn, Tegene; Kruger, T.P.J. (Tjaart); Damena, Tadewos; Mmereki, Baagi T.; Ngwira, Kennedy J.; Zachariah, Matshediso

Therapeutic switching of metformin using heteroleptic Cu(II) and Zn(II) complexes : a combined experimental and computational study

dc.contributor.author	Alem, Mamaru B.
dc.contributor.author	Koobotse, Moses O.
dc.contributor.author	Demissie, Taye B.
dc.contributor.author	Desalegn, Tegene
dc.contributor.author	Kruger, T.P.J. (Tjaart)
dc.contributor.author	Damena, Tadewos
dc.contributor.author	Mmereki, Baagi T.
dc.contributor.author	Ngwira, Kennedy J.
dc.contributor.author	Zachariah, Matshediso
dc.date.accessioned	2026-02-27T09:43:03Z
dc.date.available	2026-02-27T09:43:03Z
dc.date.issued	2026-02-02
dc.description.abstract	Please read abstract in the article.
dc.description.department	Physics
dc.description.librarian	hj2026
dc.description.sdg	SDG-03: Good health and well-being
dc.description.uri	https://pubs.acs.org/journal/acsodf?ref=breadcrumb
dc.identifier.citation	Alem, M.B., Koobotse, M.O,. Demissie, T.B. et al. 2026, 'Therapeutic switching of metformin using heteroleptic Cu(II) and Zn(II) complexes: a combined experimental and computational study', ACS Omega, vol. 11, no. 6, pp. 9245–9258, doi : 10.1021/acsomega.5c08757.
dc.identifier.issn	2470-1343 (online)
dc.identifier.other	10.1021/acsomega.5c08757
dc.identifier.uri	http://hdl.handle.net/2263/108680
dc.language.iso	en
dc.publisher	American Chemical Society
dc.rights	© 2026 The Authors. Published by American Chemical Society. This publication is licensed under CC-BY-NC-ND 4.0.
dc.subject	Ligands
dc.subject	Toxicity
dc.subject	Pharmaceuticals
dc.subject	Peptides and proteins
dc.subject	Metals
dc.title	Therapeutic switching of metformin using heteroleptic Cu(II) and Zn(II) complexes : a combined experimental and computational study
dc.type	Article