Lagos bat virus, an under-reported rabies-related lyssavirus

dc.contributor.authorCoertse, Jessica
dc.contributor.authorGeldenhuys, Marike
dc.contributor.authorLe Roux, Kevin
dc.contributor.authorMarkotter, Wanda
dc.contributor.emailmarike.geldenhuys@up.ac.zaen_US
dc.date.accessioned2022-09-08T13:11:42Z
dc.date.available2022-09-08T13:11:42Z
dc.date.issued2021-03-29
dc.description.abstractLagos bat virus (LBV), one of the 17 accepted viral species of the Lyssavirus genus, was the first rabies-related virus described in 1956. This virus is endemic to the African continent and is rarely encountered. There are currently four lineages, although the observed genetic diversity exceeds existing lyssavirus species demarcation criteria. Several exposures to rabid bats infected with LBV have been reported; however, no known human cases have been reported to date. This review provides the history of LBV and summarizes previous knowledge as well as new detections. Genetic diversity, pathogenesis and prevention are re-evaluated and discussed.en_US
dc.description.departmentMedical Virologyen_US
dc.description.librariandm2022en_US
dc.description.sponsorshipThis research is supported in part by the South African Research Chair Initiative (held by Wanda Markotter) of the Department of Science and Innovation and administered by the National Research Foundation of South Africa (UID: 98339). The National Research Foundation funded the equipment based at the DNA Sanger sequencing facility in the Faculty of Natural and Agricultural Sciences, University of Pretoria (UID: 78566).en_US
dc.description.urihttps://www.mdpi.com/journal/virusesen_US
dc.identifier.citationCoertse, J.; Geldenhuys, M.; le Roux, K.; Markotter, W. Lagos Bat Virus, an Under-Reported Rabies-Related Lyssavirus. Viruses 2021, 13, 576. https://doi.org/10.3390/v13040576.en_US
dc.identifier.issn1999-4915 (online)
dc.identifier.other10.3390/v13040576
dc.identifier.urihttps://repository.up.ac.za/handle/2263/87127
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.rights© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).en_US
dc.subjectLyssavirusen_US
dc.subjectBatsen_US
dc.subjectRabiesen_US
dc.subjectAfricaen_US
dc.subjectLagos bat lyssavirus (LBV)en_US
dc.subjectSouth Africa (SA)en_US
dc.titleLagos bat virus, an under-reported rabies-related lyssavirusen_US
dc.typeArticleen_US

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