The immune response in a dog to Encephalitozoon cuniculi infection

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Stewart, C.G.
Collett, M.G.
Snyman, Helena

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Published by the Government Printer, Pretoria.

Abstract

The immune response to Encephalitozoon cuniculi infection in a dog was investigated by means of the indirect fluorescent antibody test, the leucocyte migration inhibition test and the radial immunodiffusion test for serum IgG and IgM levels. Specific antibodies were detected within 7 days of infection and they persisted for 370 days. A cellmediated immune response was detected from Day 13 following infection until Day 97. Histopathological examination showed plasma cell infiltration of the kidneys, meninges, lung, bladder, smooth muscle and spleen.
The immune response to Encephalitozoon cuniculi infection in a dog was investigated by means of the indirect fluorescent antibody test, the leucocyte migration inhibition test and the radial immunodiffusion test for serum IgG and IgM levels. Specific antibodies were detected within 7 days of infection and they persisted for 370 days. A cell-mediated immune response was detected from Day 13 following infection until Day 97. Histopathological examination showed plasma cell infiltration of the kidneys, meninges, lung, bladder, smooth muscle and spleen.

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Keywords

Veterinary medicine

Sustainable Development Goals

Citation

Stewart, CG, Collet, MG & Snyman, H 1986, 'The immune response in a dog to Encephalitozoon cuniculi infection’, Onderstepoort Journal of Veterinary Research, vol. 53, no. 1, pp. 35-37.