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dc.contributor.author | Parsons, S.D.C.![]() |
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dc.contributor.author | Becks, D.![]() |
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dc.contributor.author | Vermeulen, A.![]() |
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dc.contributor.author | Hobson, M.![]() |
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dc.contributor.author | Warren, R.M.![]() |
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dc.contributor.author | Hooijberg, Emma Henriette![]() |
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dc.date.accessioned | 2024-08-15T10:55:52Z | |
dc.date.available | 2024-08-15T10:55:52Z | |
dc.date.issued | 2023-02 | |
dc.description.abstract | Angora goats in South Africa experience several syndromes that result in notable morbidity and mortality in juveniles and adults, but not kids. Insight into their causes is hampered by the lack of normal reference values for this breed, and the present study therefore aimed to characterise (1) differences in the haematology of healthy kids at birth and weaning, and (2) the haematology of apparently healthy yearlings. Selected variables were measured by blood smear analysis, and complete blood counts were performed using an ADVIA 2120i. Variables at 1, 11, and 20 weeks of age were compared using the Friedman test and associations between variables of yearlings were determined by correlation analysis. In kids, red blood cell count, mean corpuscular haemoglobin concentration (MCHC), and poikilocytosis increased over time, while mean corpuscular haemoglobin (MCH) and mean corpuscular volume (MCV) decreased. Yearlings displayed a lower MCHC, and higher haemoglobin distribution width than previously reported for goats, and these were positively correlated with poikilocytosis, as were reticulocyte counts. White cell counts of yearlings exceeded normal values previously reported for goats, with some individuals displaying remarkably high mature neutrophil counts. Changes in haemoglobin variant expression or cation and water fluxes are possible explanations for the findings in kids, while in yearlings, the associations between MCHC, HDW, poikilocytosis, and reticulocytosis suggest alterations in red cell hydration in adulthood that are associated with increased red cell turnover. These findings may prove informative in the further investigation of various clinical syndromes in this population. | en_US |
dc.description.department | Companion Animal Clinical Studies | en_US |
dc.description.librarian | am2024 | en_US |
dc.description.sdg | SDG-03:Good heatlh and well-being | en_US |
dc.description.sponsorship | The South African Medical Research Council (SAMRC) Centre for Tuberculosis Research; The Harry Crossley Foundation; The Faculty of Medicine and Health Sciences Undergraduate Research Project Fund of Stellenbosch University. | en_US |
dc.description.uri | http://www.jsava.co.za | en_US |
dc.identifier.citation | Parsons, S.D.C., Becks, D., Vermeulen, A. et al. 2023, 'Poikilocytosis of Angora goats is associated with erythrocyte density and reticulocytosis', Journal of the South African Veterinary Association, vol. 94. no. 1, pp. 42-53. https://DOI.org/10.36303/JSAVA.547. | en_US |
dc.identifier.issn | 2224-9435 (print) | |
dc.identifier.issn | 1019-9128 (online) | |
dc.identifier.other | 10.36303/JSAVA.547 | |
dc.identifier.uri | http://hdl.handle.net/2263/97663 | |
dc.language.iso | en | en_US |
dc.publisher | MedPharm Publications | en_US |
dc.rights | © 2023 The Author(s). Open Access article distributed under the terms of the Creative Commons License [CC BY-NC 3.0]. | en_US |
dc.subject | Angora goat | en_US |
dc.subject | Mean corpuscular haemoglobin concentration (MCHC) | en_US |
dc.subject | Mean corpuscular volume (MCV) | en_US |
dc.subject | Poikilocytosis | en_US |
dc.subject | Reticulocytosis | en_US |
dc.subject | SDG-03: Good health and well-being | en_US |
dc.title | Poikilocytosis of Angora goats is associated with erythrocyte density and reticulocytosis | en_US |
dc.type | Article | en_US |