Due to flow maldistribution, the condensation and evaporation flow patterns in multiport minichannels are considerably different from single minichannels or macrochannels. This article compiled the friction pressure drop data from experimental phase-change investigations in multiport minichannel condensers and evaporators over the past two decades. The data was reduced to friction pressure gradients, and a new two-phase multiplier was proposed for estimating the phase-change pressure drop in multiport condensers and evaporators. Thirteen hundred and forty-four condensation pressure drop and six hundred and twenty-three evaporation pressure drop data from twenty-nine studies were correlated to yield four predictive two-phase multiplier equations in the laminar and turbulent flow regimes. The predictive correlations fit 67% of the laminar condensation and 80% of the turbulent pressure drop data within ±50%. Further, 57% of the laminar evaporation and 100% of the turbulent evaporation pressure drop data were fit within ±50%. The correlations were compared with widely published correlations and were a significant improvement. Meta-analysis revealed that multiport minichannels are most effective for reducing turbulent flow condensation pressure drop and laminar flow evaporation pressure drop. The compiled data and presented correlations and analysis should be helpful to the process, electronics packaging, aviation, and aerospace industries designing compact, lightweight, and high-efficiency condensers, and evaporators.