SARS-CoV-2 reverse zoonoses to pumas and lions, South Africa

Show simple item record Koeppel, Katja Natalie Mendes, Adriano Strydom, Amy Rotherham, Lia Mulumba, Misheck Venter, Marietjie 2023-03-22T06:44:30Z 2023-03-22T06:44:30Z 2022-01-11
dc.description SUPPLEMENTARY MATERIAL : TABLE S1: PCR and serological results from direct and indirect human contacts with infected lions, TABLE S2: Detection of SARS-CoV-2 E and RdRp genes from lion faecal samples in Ct values, FIGURE S1: Bayesian phylogenetic inference of whole genome sequences detected in lions and humans. en_US
dc.description.abstract Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species will mitigate the risk to humans and wildlife occurring in Africa. Here we report infection of an exotic puma (July 2020) and three African lions (July 2021) in the same private zoo in Johannesburg, South Africa. One Health genomic surveillance identified transmission of a Delta variant from a zookeeper to the three lions, similar to those circulating in humans in South Africa. One lion developed pneumonia while the other cases had mild infection. Both the puma and lions remained positive for SARS-CoV-2 RNA for up to 7 weeks. en_US
dc.description.department Centre for Veterinary Wildlife Studies en_US
dc.description.department Medical Virology en_US
dc.description.department Production Animal Studies en_US
dc.description.librarian am2023 en_US
dc.description.sponsorship The G7 Global Health fund supplementary funding for SARS-CoV-2 through the Robert Koch Institute for the African Network for improved diagnostics and epidemiology of common and emerging infections. en_US
dc.description.uri en_US
dc.identifier.citation Koeppel, K.N.; Mendes, A.; Strydom, A.; Rotherham, L.; Mulumba, M.; Venter, M. SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa. Viruses 2022, 14, 120. en_US
dc.identifier.issn 1999-4915 (online)
dc.identifier.other 10.3390/v14010120
dc.language.iso en en_US
dc.publisher MDPI en_US
dc.rights © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. en_US
dc.subject Reverse zoonosis en_US
dc.subject Wildlife en_US
dc.subject Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) en_US
dc.subject Lion (Panthera leo) en_US
dc.subject Puma (Puma concolor) en_US
dc.title SARS-CoV-2 reverse zoonoses to pumas and lions, South Africa en_US
dc.type Article en_US

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