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dc.contributor.author | Koeppel, Katja Natalie![]() |
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dc.contributor.author | Mendes, Adriano![]() |
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dc.contributor.author | Strydom, Amy![]() |
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dc.contributor.author | Rotherham, Lia![]() |
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dc.contributor.author | Mulumba, Misheck![]() |
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dc.contributor.author | Venter, Marietjie![]() |
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dc.date.accessioned | 2023-03-22T06:44:30Z | |
dc.date.available | 2023-03-22T06:44:30Z | |
dc.date.issued | 2022-01-11 | |
dc.description | SUPPLEMENTARY MATERIAL : TABLE S1: PCR and serological results from direct and indirect human contacts with infected lions, TABLE S2: Detection of SARS-CoV-2 E and RdRp genes from lion faecal samples in Ct values, FIGURE S1: Bayesian phylogenetic inference of whole genome sequences detected in lions and humans. | en_US |
dc.description.abstract | Reverse-zoonotic infections of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) from humans to wildlife species internationally raise concern over the emergence of new variants in animals. A better understanding of the transmission dynamics and pathogenesis in susceptible species will mitigate the risk to humans and wildlife occurring in Africa. Here we report infection of an exotic puma (July 2020) and three African lions (July 2021) in the same private zoo in Johannesburg, South Africa. One Health genomic surveillance identified transmission of a Delta variant from a zookeeper to the three lions, similar to those circulating in humans in South Africa. One lion developed pneumonia while the other cases had mild infection. Both the puma and lions remained positive for SARS-CoV-2 RNA for up to 7 weeks. | en_US |
dc.description.department | Centre for Veterinary Wildlife Studies | en_US |
dc.description.department | Medical Virology | en_US |
dc.description.department | Production Animal Studies | en_US |
dc.description.librarian | am2023 | en_US |
dc.description.sponsorship | The G7 Global Health fund supplementary funding for SARS-CoV-2 through the Robert Koch Institute for the African Network for improved diagnostics and epidemiology of common and emerging infections. | en_US |
dc.description.uri | https://www.mdpi.com/journal/viruses | en_US |
dc.identifier.citation | Koeppel, K.N.; Mendes, A.; Strydom, A.; Rotherham, L.; Mulumba, M.; Venter, M. SARS-CoV-2 Reverse Zoonoses to Pumas and Lions, South Africa. Viruses 2022, 14, 120. https://DOI.org/10.3390/v14010120. | en_US |
dc.identifier.issn | 1999-4915 (online) | |
dc.identifier.other | 10.3390/v14010120 | |
dc.identifier.uri | http://hdl.handle.net/2263/90170 | |
dc.language.iso | en | en_US |
dc.publisher | MDPI | en_US |
dc.rights | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. | en_US |
dc.subject | Reverse zoonosis | en_US |
dc.subject | Wildlife | en_US |
dc.subject | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) | en_US |
dc.subject | Lion (Panthera leo) | en_US |
dc.subject | Puma (Puma concolor) | en_US |
dc.title | SARS-CoV-2 reverse zoonoses to pumas and lions, South Africa | en_US |
dc.type | Article | en_US |