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dc.contributor.author | Van Heerden, Bertus | |
dc.contributor.author | Vickers, Nicholas A. | |
dc.contributor.author | Kruger, T.P.J. (Tjaart) | |
dc.contributor.author | Andersson, Sean B. | |
dc.date.accessioned | 2022-12-15T08:52:30Z | |
dc.date.issued | 2022-07 | |
dc.description.abstract | Real-time feedback-driven single-particle tracking (RT-FD-SPT) is a class of techniques in the field of single-particle tracking that uses feedback control to keep a particle of interest in a detection volume. These methods provide high spatiotemporal resolution on particle dynamics and allow for concurrent spectroscopic measurements. This review article begins with a survey of existing techniques and of applications where RT-FD-SPT has played an important role. Each of the core components of RT-FD-SPT are systematically discussed in order to develop an understanding of the trade-offs that must be made in algorithm design and to create a clear picture of the important differences, advantages, and drawbacks of existing approaches. These components are feedback tracking and control, ranging from simple proportional-integral-derivative control to advanced nonlinear techniques, estimation to determine particle location from the measured data, including both online and offline algorithms, and techniques for calibrating and characterizing different RT-FD-SPT methods. Then a collection of metrics for RT-FD-SPT is introduced to help guide experimentalists in selecting a method for their particular application and to help reveal where there are gaps in the techniques that represent opportunities for further development. Finally, this review is concluded with a discussion on future perspectives in the field. | en_US |
dc.description.department | Forestry and Agricultural Biotechnology Institute (FABI) | en_US |
dc.description.department | Physics | en_US |
dc.description.embargo | 2023-06-27 | |
dc.description.librarian | hj2022 | en_US |
dc.description.sponsorship | The National Institute of General Medical Sciences and the South African National Research Foundation. | en_US |
dc.description.uri | https://onlinelibrary.wiley.com/journal/16136829 | en_US |
dc.identifier.citation | Van Heerden, B., Vickers, N.A., Krüger, T.P.J. et al. 2022, 'Real-time feedback-driven single-particle tracking: a survey and perspective', Small, vol. 18, no. 29, art. 2107024, pp. 1-25, doi : 10.1002/smll.202107024. | en_US |
dc.identifier.issn | 1613-6829 (online) | |
dc.identifier.issn | 1613-6810 (print) | |
dc.identifier.other | 10.1002/smll.202107024 | |
dc.identifier.uri | https://repository.up.ac.za/handle/2263/88823 | |
dc.language.iso | en | en_US |
dc.publisher | Wiley | en_US |
dc.rights | © 2022 Wiley-VCH GmbH. This is the pre-peer reviewed version of the following article : 'Real-time feedback-driven single-particle tracking: a survey and perspective', Small, vol. 18, no. 29, art. 2107024, pp. 1-25, 2022, doi : 10.1002/smll.202107024. The definite version is available at : https://onlinelibrary.wiley.com/journal/16136829. | en_US |
dc.subject | Active feedback tracking | en_US |
dc.subject | Single molecule spectroscopy | en_US |
dc.subject | Single-particle tracking | en_US |
dc.subject | Real-time feedback-driven single-particle tracking (RT-FD-SPT) | en_US |
dc.title | Real-time feedback-driven single-particle tracking : a survey and perspective | en_US |
dc.type | Postprint Article | en_US |