Abstract:
The advances in mobile technologies and applications are driving the transformation in health services delivery
globally. Mobile phone penetration is increasing exponentially in low-and middle-income countries, hence using
mobile phones for healthcare services could reach more people in resource-limited settings than the traditional
forms of healthcare provision. The review presents recent literature on facilitators and barriers of implementing
mHealth for disease screening and treatment support in low-and middle-income countries. We searched for
relevant literature from the following electronic databases: MEDLINE; CINAHL with full text via EBSCOhost;
Science Direct; PubMed; Google Scholar and Web of Science using the keywords for relevant studies. We searched
for published studies from 2015 to August 2020 with no language limitations. A total of 721 articles identified,
125 articles met the inclusion criteria and were included in the qualitative synthesis. The review demonstrates
relevant facilitators for the implementation of mHealth, which includes knowledge, attitudes, and perceptions of
stakeholders on the use of mHealth and the performance of mHealth for disease diagnosis in low and-middleincome
countries. Barriers and challenges hindering the implementation of mHealth applications were also
identified. We proposed a framework for improving the implementation of mHealth for disease screening and
treatment support in low-and middle-income countries.