• T. wallichii grows in the dry areas of the south-western Cape on sandy or
stony soils lower down on the slopes of mountains and hills, whereas
• T. grandiflorus only grows in the winter rainfall area of the Cape where it
can be found on the western slopes of mountains of the Cape Peninsula
and northwards along the coast to Clanwilliam.
General: Succulent to semi-succulent deciduous plants.
Leaves: Succulent leaves which leave woody, protuberant scars when they die down and fall off.
Flowers: 5-merous. Produced after the leaves have fallen off. T. wallichii flowers December - January, T. grandiflorus flowers January - March.
Cumulative neurotoxic bufadienolides such a cotyledoside
Krimpsiekte – cumulative bufadienolides
• Krimpsiekte is basically a paretic syndrome.
• Affected animals lag behind the flock.
• When forced to move, they tire easily and lie down or stand trembling, typically
with the feet together, the back arched and the head low.
• The neck may be twisted and the head may dangle loosely as the animal walks.
• The incidence of krimpsiekte is highest in goats, then in sheep.
Thalamic vacuolisation has been reported with krimpsiekte.
• No specific treatment for krimpsiekte.
• Treatment is symptomatic and supportive.
• Stock may recover with good nursing care.
Colour photos. Final web-ready size: JPEG. Photo 1: 14.6 kb, 72 ppi; Photo 2: 11.1 kb, 72 ppi; Photo 3: 23.9 kb, 96 ppi; Photo 4: 21.7 kb, 72 ppi; Photo 5: 9.66 kb, 300 ppi; Photo 6: 30.3 kb, 1350 ppi. Original TIFF file housed at the Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology, University of Pretoria.