Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites

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dc.contributor.author Niemand, Jandeli
dc.contributor.author Van Biljon, Riette Andele
dc.contributor.author Van der Watt, Mariette Elizabeth
dc.contributor.author Van Heerden, Ashleigh
dc.contributor.author Reader, Janette
dc.contributor.author Van Wyk, Roelof Daniel Jacobus
dc.contributor.author Orchard, Lindsey M.
dc.contributor.author Chibale, Kelly
dc.contributor.author Llinas, Manuel
dc.contributor.author Birkholtz, Lyn-Marie
dc.date.accessioned 2021-12-13T05:41:00Z
dc.date.available 2021-12-13T05:41:00Z
dc.date.issued 2021-09
dc.description Supplementary material 1: Figure S1: MMV390048 or MMV642943 chemical structures. Figure S2: Verification of microarray-identified differential gene expression with qPCR analyses (PDF) en_ZA
dc.description Supplementary material 2: Additional Excel File provided with a summary of the full gene expression data set with GO and cluster analyses (XLSX) en_ZA
dc.description.abstract Please read abstract in the article. en_ZA
dc.description.department Biochemistry en_ZA
dc.description.department Genetics en_ZA
dc.description.department Microbiology and Plant Pathology en_ZA
dc.description.department UP Centre for Sustainable Malaria Control (UP CSMC) en_ZA
dc.description.librarian hj2021 en_ZA
dc.description.sponsorship The South African Medical Research Council and the Department of Science and Innovation South African Research Chairs Initiative Grants managed by the National Research Foundation and the International Society of Infectious diseases Small Grants program. en_ZA
dc.description.uri https://pubs.acs.org/journal/aidcbc en_ZA
dc.identifier.citation Niemand, J., Van Biljon, R., Van Der Watt, M. et al. 2021, 'Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites', ACS Infectious Diseases, vol. 7. no. 10, pp. 2904-2916. en_ZA
dc.identifier.issn 2373-8227 (print)
dc.identifier.issn 2373-8227 (online)
dc.identifier.other 10.1021/acsinfecdis.1c00373
dc.identifier.uri http://hdl.handle.net/2263/83028
dc.language.iso en en_ZA
dc.publisher American Chemical Society en_ZA
dc.rights © 2021 The Authors. Published by American Chemical Society en_ZA
dc.subject Gametocyte en_ZA
dc.subject Drug response en_ZA
dc.subject Kinase en_ZA
dc.subject Stage-specific en_ZA
dc.subject Chemogenomic en_ZA
dc.subject Plasmodium en_ZA
dc.title Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites en_ZA
dc.type Article en_ZA


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