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dc.contributor.author | Simpson, Gregory J.G.![]() |
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dc.contributor.author | Quesada, Fabiola![]() |
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dc.contributor.author | Chatterjee, Pranab![]() |
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dc.contributor.author | Kakkar, Manish![]() |
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dc.contributor.author | Chersich, Matthew F.![]() |
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dc.contributor.author | Thys, Severine![]() |
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dc.date.accessioned | 2021-12-08T07:08:48Z | |
dc.date.available | 2021-12-08T07:08:48Z | |
dc.date.issued | 2021-04 | |
dc.description | Supplementary file 1. Expert Questionnaire SA | en_ZA |
dc.description | Supplementary file 2. Stakeholder input | en_ZA |
dc.description.abstract | BACKGROUND : Zoonoses pose major threats to the health of humans, domestic animals and wildlife, as seen in the COVID-19 pandemic. Zoonoses are the commonest source of emerging human infections and inter-species transmission is facilitated by anthropogenic factors such as encroachment and destruction of wilderness areas, wildlife trafficking and climate change. South Africa was selected for a ‘One Health’ study to identify research priorities for control of zoonoses due to its complex disease burden and an overstretched health system. METHODS : A multidisciplinary group of 18 experts identified priority zoonotic diseases, knowledge gaps and proposed research priorities for the next 5 y. Each priority was scored using predefined criteria by another group of five experts and then weighted by a reference group (n=28) and the 18 experts. RESULTS : Seventeen diseases were mentioned with the top five being rabies (14/18), TB (13/18), brucellosis (11/18), Rift Valley fever (9/11) and cysticercosis (6/18). In total, 97 specific research priorities were listed, with the majority on basic epidemiological research (n=57), such as measuring the burden of various zoonoses (n=24), followed by 20 on development of new interventions. The highest research priority score was for improving existing interventions (0.77/1.0), followed by health policy and systems research (0.72/1.0). CONCLUSION : Future zoonotic research should improve understanding of zoonotic burden and risk factors and new interventions in public health. People with limited rural services, immunocompromised, in informal settlements and high-risk occupations, should be the highest research priority. | en_ZA |
dc.description.department | Production Animal Studies | en_ZA |
dc.description.librarian | hj2021 | en_ZA |
dc.description.sponsorship | The Belgian Directorate General for Development Cooperation and Humanitarian Aid | en_ZA |
dc.description.uri | http://trstmh.oxfordjournals.org | en_ZA |
dc.identifier.citation | Simpson, G., Quesada, F., Chatterjee, P. et al. Research priorities for control of zoonoses in South Africa. Transactions of the Royal Society of Tropical Medicine and Hygiene 2021 Apr 1 : trab039. Published online 2021 Apr 1. doi: 10.1093/trstmh/trab039. | en_ZA |
dc.identifier.issn | 0035-9203 (print) | |
dc.identifier.issn | 1878-3503 (online) | |
dc.identifier.other | 10.1093/trstmh/trab039 | |
dc.identifier.uri | http://hdl.handle.net/2263/82992 | |
dc.language.iso | en | en_ZA |
dc.publisher | Oxford University Press | en_ZA |
dc.rights | © The Author(s) 2020. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. | en_ZA |
dc.subject | Disease burden | en_ZA |
dc.subject | One Health | en_ZA |
dc.subject | Research priorities | en_ZA |
dc.subject | South Africa (SA) | en_ZA |
dc.subject | Zoonoses | en_ZA |
dc.subject.other | Veterinary science articles SDG-03 | en_ZA |
dc.subject.other | SDG-03: Good health and well-being | |
dc.title | Research priorities for control of zoonoses in South Africa | en_ZA |
dc.type | Postprint Article | en_ZA |