Willingness of people with Type 2 diabetes to start insulin therapy : evidence from the South African Tshwane Insulin Project (TIP)

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dc.contributor.author Ngassa Piotie, Patrick
dc.contributor.author Wood, Paola Silvia
dc.contributor.author Webb, Elizabeth M.
dc.contributor.author Marcus, Tessa S.
dc.contributor.author Rheeder, Paul
dc.date.accessioned 2021-05-07T12:00:00Z
dc.date.issued 2020-10
dc.description.abstract AIMS : To determine factors associated with ‘hypothetical willingness’ to start insulin among people with Type 2 diabetes (T2DM). METHODS : A quantitative cross-sectional study with insulin-naïve T2DM patients at 23 primary care facilities in the Tshwane Metropolitan Municipality. Data collected included demographic and clinical data, willingness to start insulin, attitudes and barriers to insulin therapy. Factors associated with unwillingness to start insulin therapy were explored using a multivariable logistic regression model. RESULTS : Of 468 T2DM study patients (mean age 57.2, SD = 11.3 years), more than half (51.9%) expressed unwillingness to starting insulin therapy. Unwillingness was associated with negative attitudes (OR = 1.32, 95% CI = 1.12–1.55, p = 0.001) and reluctance (OR = 1.41, 95% CI = 1.27–1.57, p < 0.001) rather than age, sex, education or diabetes duration. The strongest reasons for patient unwillingness were injection anxieties, fear of needles, insufficient knowledge of insulin, feeling unable to cope with insulin and concerns about out-of-pocket costs. CONCLUSIONS : The prospect of insulin therapy disturbs patients’ sense of self and their psychological wellbeing. The high prevalence of psychological insulin resistance among these T2DM patients needs to be addressed for effective diabetes management. en_ZA
dc.description.department Family Medicine en_ZA
dc.description.department Internal Medicine en_ZA
dc.description.department Physiology en_ZA
dc.description.department School of Health Systems and Public Health (SHSPH) en_ZA
dc.description.embargo 2021-08-11
dc.description.librarian hj2021 en_ZA
dc.description.sponsorship The Lilly Global Health Partnership en_ZA
dc.description.uri http://www.elsevier.com/locate/diabres en_ZA
dc.identifier.citation Ngassa Piotie, P., Wood, P., Webb, E.M. et al. 2020, 'Willingness of people with Type 2 diabetes to start insulin therapy : evidence from the South African Tshwane Insulin Project (TIP)', Diabetes Research and Clinical Practice, vol. 168, art. 108366, pp. 1-10. en_ZA
dc.identifier.issn 0168-8227
dc.identifier.other 10.1016/j.diabres.2020.108366
dc.identifier.uri http://hdl.handle.net/2263/79812
dc.language.iso en en_ZA
dc.publisher Elsevier en_ZA
dc.rights © 2020 Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Diabetes Research and Clinical Practice. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Diabetes Research and Clinical Practice, vol. 168, art. 108366, pp. 1-10, 2020. doi : 10.1016/j.diabres.2020.108366. en_ZA
dc.subject Diabetes mellitus en_ZA
dc.subject Type 2 diabetes mellitus (T2DM) en_ZA
dc.subject Insulin therapy en_ZA
dc.subject Willingness en_ZA
dc.subject Psychological insulin resistance en_ZA
dc.subject Primary care en_ZA
dc.title Willingness of people with Type 2 diabetes to start insulin therapy : evidence from the South African Tshwane Insulin Project (TIP) en_ZA
dc.type Postprint Article en_ZA


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