Epithelioid haemangioma (angiolymphoid hyperplasia with eosinophilia subtype) involving the vermillion border of the lower lip

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Authors

Robinson, Liam
Lebaka, C.S. (Chidinyane)
Van Heerden, Willem Francois Petrus

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Publisher

Wiley

Abstract

Epithelioid vascular tumours include benign epithelioid haemangioma (EH) and epithelioid angiomatous nodule, low‐grade malignant epithelioid haemangioendothelioma and high‐grade epithelioid angiosarcoma. These tumours share epithelioid cell morphologies and intracytoplasmic vacuoles, with distinction based on differing architectural and nuclear features. This report highlights a case of EH, angiolymphoid hyperplasia with eosinophilia subtype, involving the vermillion border of the lower lip in an elderly female patient. The clinical and histological features, differential diagnosis, aetiopathogenesis, molecular basis and treatment options are discussed as part of a comprehensive review of this rare entity.

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Keywords

Epithelioid vascular tumours, Epithelioid haemangioma (EH), Epithelioid angiomatous nodule, Epithelioid haemangioendothelioma, Epithelioid angiosarcoma, Angiolymphoid hyperplasia with eosinophilia (ALHE), Cellular subtypes

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Citation

Robinson, L., Lebaka, C.S., Heerden, W.F.P. Epithelioid haemangioma (angiolymphoid hyperplasia with eosinophilia subtype) involving the vermillion border of the lower lip. Oral Surgery 2022;15(1):81-87. https://doi.org/10.1111/ors.12588.