dc.contributor.author |
Deleu, Anne-Leen
|
|
dc.contributor.author |
Sathekge, Machaba Junior
|
|
dc.contributor.author |
Maes, Alex
|
|
dc.contributor.author |
De Spiegeleer, Bart
|
|
dc.contributor.author |
Sathekge, Mike Machaba
|
|
dc.contributor.author |
Van de Wiele, Christophe
|
|
dc.date.accessioned |
2021-02-20T06:02:54Z |
|
dc.date.available |
2021-02-20T06:02:54Z |
|
dc.date.issued |
2020-08 |
|
dc.description.abstract |
Radiomics or textural feature extraction obtained from positron emission tomography
(PET) images through complex mathematical models of the spatial relationship between multiple
image voxels is currently emerging as a new tool for assessing intra-tumoral heterogeneity in medical
imaging. In this paper, available literature on texture analysis using FDG PET imaging in patients
suffering from tumors of the gastro-intestinal tract is reviewed. While texture analysis of FDG PET
images appears clinically promising, due to the lack of technical specifications, a large variability in
the implemented methodology used for texture analysis and lack of statistical robustness, at present,
no firm conclusions can be drawn regarding the predictive or prognostic value of FDG PET texture
analysis derived indices in patients suffering from gastro-enterologic tumors. In order to move
forward in this field, a harmonized image acquisition and processing protocol as well as a harmonized
protocol for texture analysis of tumor volumes, allowing multi-center studies excluding statistical
biases should be considered. Furthermore, the complementary and additional value of CT-imaging,
as part of the PET/CT imaging technique, warrants exploration. |
en_ZA |
dc.description.department |
Nuclear Medicine |
en_ZA |
dc.description.librarian |
pm2021 |
en_ZA |
dc.description.uri |
http://www.mdpi.com/journal/biomedicines |
en_ZA |
dc.identifier.citation |
Deleu, A-L., Sathekge, M.J., Maes, A. et al. 2020, 'Characterization of FDG PET images using texture analysis in tumors of the gastro-intestinal tract: a review', BioMedicines, vol. 8, no. 9, art. 304, pp. 1-13. |
en_ZA |
dc.identifier.issn |
2227-9059 (online) |
|
dc.identifier.other |
10.3390/biomedicines8090304 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/78784 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
MDPI |
en_ZA |
dc.rights |
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access
article distributed under the terms and conditions of the Creative Commons Attribution
(CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
en_ZA |
dc.subject |
Radiomics |
en_ZA |
dc.subject |
Gastro-intestinal cancer |
en_ZA |
dc.subject |
Textural feature extraction |
en_ZA |
dc.subject |
Positron emission tomography (PET) |
en_ZA |
dc.subject |
Intra-tumoral heterogeneity |
en_ZA |
dc.subject |
Medical imaging |
en_ZA |
dc.subject |
Fluorodeoxyglucose-positron emission tomography (FDG PET) |
en_ZA |
dc.title |
Characterization of FDG PET images using texture analysis in tumors of the gastro-intestinal tract : a review |
en_ZA |
dc.type |
Article |
en_ZA |