Clinical trial data management in environmental health tailored for an African setting

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dc.contributor.author Albers, Patricia Nicole
dc.contributor.author Wright, Caradee Yael
dc.date.accessioned 2020-05-28T14:47:34Z
dc.date.available 2020-05-28T14:47:34Z
dc.date.issued 2020-01-08
dc.description.abstract Clinical trial data management tools are widely available—some free to access and others relatively expensive, particularly for low- and middle-income countries. Such tools also do not always permit adaptation for local conditions nor include options to capture environmental and meteorological data. In the context of climate change and pressing environmental health threats, more studies that aim to assess the impacts of environmental change on public health are being carried out. Here, using freely available software, we tailor-made a clinical trial data management tool that managed all aspects of an intervention-based clinical trial to assess the impact of personal solar ultraviolet radiation exposure on vaccine e ectiveness. Data captured and associated procedures included patient data, scheduling, reporting, analysis and data management. Moreover, patient enrolment, recruitment, follow-up and decision-making in response to patient data were managed. Given the multidisciplinary study approach, the tool also managed all environmental and meteorological data for the rural African study site. Application of the tool ensured e cient communication between rural sites, a relatively high overall participant response rate (87%) and minimal loss to follow-up. This study suggests that it is possible to tailor-make a clinical trial data management tool for environmental and public health studies. en_ZA
dc.description.department Geography, Geoinformatics and Meteorology en_ZA
dc.description.librarian am2020 en_ZA
dc.description.sponsorship The National Research Foundation (NRF) of South Africa and the South African Medical Research Council (SAMRC). en_ZA
dc.description.uri www.mdpi.com/journal/ijerph en_ZA
dc.identifier.citation Albers, P.N. & Wright, C.Y. 2020, 'Clinical trial data management in environmental health tailored for an African setting', International Journal of Environmental Research and Public Health, vol. 17, no. 2, art. 402, pp. 1-15. en_ZA
dc.identifier.issn 1660-4601 (online)
dc.identifier.other 10.3390/ijerph17020402
dc.identifier.uri http://hdl.handle.net/2263/74778
dc.language.iso en en_ZA
dc.publisher MDPI en_ZA
dc.rights © 2020 by the authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. en_ZA
dc.subject Data en_ZA
dc.subject Methods en_ZA
dc.subject Clinical trial en_ZA
dc.subject Environmental health en_ZA
dc.subject Sun exposure en_ZA
dc.subject Public health en_ZA
dc.subject Python en_ZA
dc.subject SQLite en_ZA
dc.subject South Africa (SA) en_ZA
dc.subject Data management en_ZA
dc.title Clinical trial data management in environmental health tailored for an African setting en_ZA
dc.type Article en_ZA


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