Genotypic and phenotypic diversity of Mycobacterium tuberculosis strains in patients with concomitant pulmonary and extra-pulmonary tuberculosis

Sibandze, Busizwe Busizwe

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dc.contributor.advisor	Peters, Remco P.H.
dc.contributor.coadvisor	Mbelle, Nontombi Marylucy
dc.contributor.postgraduate	Sibandze, Busizwe Busizwe
dc.date.accessioned	2019-12-13T08:07:32Z
dc.date.available	2019-12-13T08:07:32Z
dc.date.created	2019/09/06
dc.date.issued	2019
dc.description	Dissertation (MSc)--University of Pretoria, 2019.
dc.description.abstract	future, more robust or higher-resolution genomic typing tools, such as target Next Generation Sequencing (t-NGS) or metagenomic analysis are recommended to improve our understanding of the complexity of infections and for detection of both minority and major variants within extrapulmonary and pulmonary specimens for better estimation of the extent of M. tuberculosis genotypic and phenotypic heterogeneity.
dc.description.availability	Unrestricted
dc.description.degree	MSc
dc.description.department	Medical Microbiology
dc.identifier.citation	Sibandze, BB 2019, Genotypic and phenotypic diversity of Mycobacterium tuberculosis strains in patients with concomitant pulmonary and extra-pulmonary tuberculosis, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/72686>
dc.identifier.other	S2019
dc.identifier.uri	http://hdl.handle.net/2263/72686
dc.language.iso	en
dc.publisher	University of Pretoria
dc.rights	© 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
dc.subject	UCTD
dc.subject	Tuberculosis
dc.subject	Public Health
dc.subject	Metagenomic analysis
dc.subject	Genomic typing tools
dc.subject	Molecular diagnostics
dc.subject	Health Risks
dc.subject	Pulmonary specimens
dc.subject	Genotypic heterogeneity
dc.subject	Phenotypic heterogeneity
dc.subject.other	Health sciences theses SDG-03
dc.subject.other	SDG-03: Good health and well-being
dc.subject.other	Health sciences theses SDG-10
dc.subject.other	SDG-10: Reduced inequalities
dc.subject.other	Health sciences theses SDG-17
dc.subject.other	SDG-17: Partnerships for the goals
dc.title	Genotypic and phenotypic diversity of Mycobacterium tuberculosis strains in patients with concomitant pulmonary and extra-pulmonary tuberculosis
dc.type	Dissertation