Cutaneous tuberculosis in HIV-infected individuals : lessons learnt from a case series

Show simple item record Tshisevhe, V.S. Mbelle, Nontombi Marylucy Peters, Remco P.H. 2019-08-22T14:57:16Z 2019-08-22T14:57:16Z 2019-03-12
dc.description.abstract INTRODUCTION : Extrapulmonary tuberculosis (TB) causes a significant burden of disease worldwide, especially among HIV-infected individuals and those with other immunosuppressive conditions. Cutaneous TB is an important manifestation of extrapulmonary TB but is uncommonly reported in South Africa despite the high burden of HIV and TB co-infection. There is a paucity of published data on clinical presentation and outcome of cutaneous TB in this context. Raising awareness of this condition among clinicians is imperative to improve early diagnosis and optimise treatment outcomes. PATIENT PRESENTATION : In this series, we present three cases of cutaneous TB, two adults and one child, referred to a tertiary hospital from two primary healthcare centres and from a general practitioner. We demonstrate that the clinical presentation is diverse, ranging from papular lesions to abscesses, and that concordant pulmonary TB may be present. MANAGEMENT : In particular, we show the importance of performing diagnostic procedures (e.g. aspiration) in individuals presenting with an abscess that does not respond to broad spectrum antimicrobial treatment, particularly in those with advanced immunosuppression. OUTCOME AND CONCLUSION : The outcome of our three patients was poor, highlighting the need for earlier diagnosis in this WHO Stage 4 condition and intensive management of clinical cases. en_ZA
dc.description.department Medical Microbiology en_ZA
dc.description.librarian am2019 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Tshisevhe V, Mbelle N, Peters RPH. Cutaneous tuberculosis in HIV-infected individuals: Lessons learnt from a case series. Southern African Journal of HIV Medicine 2019;20(1), a895. en_ZA
dc.identifier.issn 1608-9693 (print)
dc.identifier.issn 2078-6751 (online)
dc.identifier.other 10.4102/ sajhivmed.v20i1.895
dc.language.iso en en_ZA
dc.publisher AOSIS Open Journals en_ZA
dc.rights © 2019. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. en_ZA
dc.subject HIV-medicine en_ZA
dc.subject Retro-viral disease en_ZA
dc.subject Mycobacteria en_ZA
dc.subject Multidrug-resistant (MDR) en_ZA
dc.subject Cutaneous tuberculosis en_ZA
dc.subject Cutaneous disease en_ZA
dc.subject Immunocompromised en_ZA
dc.subject Human immunodeficiency virus (HIV) en_ZA
dc.subject Tuberculosis (TB) en_ZA
dc.title Cutaneous tuberculosis in HIV-infected individuals : lessons learnt from a case series en_ZA
dc.type Article en_ZA

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