Informal settlements are a common occurrence in the South African landscape. These settlements are not planned and therefore lack conventional urban characteristics, such as street names and a regular grid or block structure, which are useful aids during wayfinding. As a result, it is difficult to navigate through such a settlement or to provide directions to a specific destination. The lack of street names also implies that directions provided by others play a more important role. In this paper, we present the results of a qualitative between-subjects study that assessed individuals’ wayfinding efficiency when using different types of directions in an informal settlement. Participants were divided into two groups of six participants each (3 males and 3 females). Two sets of directions were constructed for the same route, one based on left-right turn descriptors and landmarks, and the second based on cardinal directions and distances. The performance of participants was measured for each set of directions. Earlier studies reported that people preferred left-right directions but performed better when using cardinal directions. The results of our study show the opposite. We think that this is due to the lack of regular wayfinding aids in informal settlements, but further studies are required to confirm this. The results of our study are interesting for developers of navigational tools aimed at addressing the needs of people in informal settlements.