One of the main implications of the push for transition from the monoculture of Eurocentric scientific knowledge towards the ecology of knowledge is to force us to pose the question: what does a decolonial turn in International Relations (IR) entail? This article grapples with this question in light of growing demands for a decolonial turn in knowledge and power. The aim is to meditate on this question with a view to open up new avenues for a structured conversation on decolonising IR and its theory. This imperative to decolonise is linked to the question of epistemic justice with implications for the epistemological structure underpinning IR, methodological frameworks for the study of IR, theoretical outlines and the teaching of the discipline. Epistemic justice is a necessity alongside historical justice for those on the margins of a world system constructed with the help of imperialism, systematic enslavement and colonialism. This article discusses the question of the decolonial turn in IR in the hope of stimulating debates on the views of the margins regarding the present state and the future of this area of knowledge, and thus move us closer to an ecology of knowledge and power.