Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009-2011

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dc.contributor.author Hellferscee, Orienka
dc.contributor.author Treurnicht, Florette K.
dc.contributor.author Tempia, Stefano
dc.contributor.author Variava, Ebrahim
dc.contributor.author Dawood, Halima
dc.contributor.author Kahn, Kathleen
dc.contributor.author Cohen, Adam L.
dc.contributor.author Pretorius, Marthi A.
dc.contributor.author Cohen, Cheryl
dc.contributor.author Madhi, Shabir A.
dc.contributor.author Venter, Marietjie
dc.date.accessioned 2018-01-24T05:18:59Z
dc.date.available 2018-01-24T05:18:59Z
dc.date.issued 2017-04
dc.description.abstract BACKGROUND : Human enteroviruses (EV) have been associated with severe acute respiratory illness (SARI) in South Africa. OBJECTIVES : We aimed to describe the molecular epidemiology of EV serotypes among patients hospitalized with SARI during 2009-2011. PATIENTS/METHODS : Study samples from patients were tested for the presence of enterovirus using a polymerase chain reaction assay. RESULTS : 8.2% (842/10 260) of SARI cases tested positive for enterovirus; 16% (7/45) were species EV-A, 44% (20/45) EV-B, 18% (8/45) EV-C and 22% (10/45) EV-D. Seventeen different EV serotypes were identified within EV-A to EV-D, of which EV-D68 (22%; 10/45) and Echovirus 3 (11%; 5/45) were the most prevalent. CONCLUSIONS : EV-D68 should be monitored in South Africa to assess the emergence of highly pathogenic strains. en_ZA
dc.description.department Medical Virology en_ZA
dc.description.librarian am2018 en_ZA
dc.description.sponsorship The United States Centers for Disease Control and Prevention, Atlanta, Georgia, USA (co-operative agreement number: 5U51IP000155). en_ZA
dc.description.uri http://www.wileyonlinelibrary.com/journal/irv en_ZA
dc.description.uri http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1750-2659 en_ZA
dc.identifier.citation Hellferscee O, Treurnicht FK, Tempia S, et al. Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009–2011. Influenza Other Respi Viruses. 2017;11:211–219. https://DOI.org/10.1111/irv.12444, en_ZA
dc.identifier.issn 1750-2640 (print)
dc.identifier.issn 1750-2659 (online)
dc.identifier.other 10.1111/irv.12444
dc.identifier.uri http://hdl.handle.net/2263/63700
dc.language.iso en en_ZA
dc.publisher Wiley Open Access en_ZA
dc.rights © 2017 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. en_ZA
dc.subject Enterovirus en_ZA
dc.subject EV-D68 en_ZA
dc.subject Pneumonia en_ZA
dc.subject South Africa (SA) en_ZA
dc.subject Human enterovirus (HEV) en_ZA
dc.subject Severe acute respiratory illness (SARI) en_ZA
dc.title Enterovirus D68 and other enterovirus serotypes identified in South African patients with severe acute respiratory illness, 2009-2011 en_ZA
dc.type Article en_ZA


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