Factors associated with the lack of antiretroviral therapy initiation among eligible HIV-positive pregnant women in Swaziland

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dc.contributor.author Chouraya, C.
dc.contributor.author Louwagie, Goedele M.C.
dc.contributor.author Nhlabatsi, B.
dc.contributor.author Mahdi, M.A.
dc.contributor.author Girdler-Brown, B.V. (Brendan)
dc.date.accessioned 2017-10-30T06:48:06Z
dc.date.available 2017-10-30T06:48:06Z
dc.date.issued 2017
dc.description.abstract BACKGROUND. Antiretroviral therapy (ART) initiation is critical for the prevention of mother-to-child transmission (PMTCT) of HIV. OBJECTIVES. To quantify factors that were barriers or facilitators to the initiation of ART in pregnant HIV-infected women in Swaziland. METHODS. We conducted a cross-sectional survey in HIV-infected women with at least one antenatal care (ANC) visit, who had delivered in maternity wards between April and August 2013 in Swaziland. Variables collected included intrapersonal, interpersonal and organisational factors. Logistic regression models were used to calculate univariate and adjusted multivariate measures of association between ART initiation and the independent variables. RESULTS. Among the 163 pregnant women who were eligible for ART, 110 (67.5%) were initiated on ART by the time of delivery. The most commonly cited reason for not initiating ART (n=53) was women not being ready to initiate life-long treatment (24.5%). On multivariate logistic regression, favourable perceptions of the benefits of ART (adjusted odds ratio (AOR) 3.04; 95% CI 1.55 - 5.96) and presence of partner support (AOR 4.75; 95% CI 2.11 - 10.67) remained significantly and independently associated with ART initiation. CONCLUSION. ART initiation among ART-eligible pregnant women in Swaziland was independently associated with the presence of partner support and favourable perceptions of the benefits of ART. Stronger counselling and education for pregnant women and male involvement strategies need to be implemented as universal life-long ART for all HIV-infected pregnant women is implemented en_ZA
dc.description.department School of Health Systems and Public Health (SHSPH) en_ZA
dc.description.librarian am2017 en_ZA
dc.description.sponsorship School of Health Systems and Public Health, University of Pretoria, Pretoria, South Africa en_ZA
dc.description.uri http://sajog.org.za/index.php/SAJOG en_ZA
dc.description.uri http://www.journals.co.za/content/journal en_ZA
dc.identifier.citation Chouraya, C., Louwagie, G., Nhlabatsi, B., Mahdi, M.A. & Girdler-Brown, B.V. 2017, 'Factors associated with the lack of antiretroviral therapy initiation among eligible HIV-positive pregnant women in Swaziland', South African Journal of Obstetrics and Gynaecology, vol. 23, no. 2, pp. 63-68. en_ZA
dc.identifier.issn 0038-2329 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.other 10.7196/SAJOG.2017.v23i2.1184
dc.identifier.uri http://hdl.handle.net/2263/62950
dc.language.iso en en_ZA
dc.publisher Health and Medical Publishing Group en_ZA
dc.rights © 2017 Health and Medical Publishing Group. This work is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0) . en_ZA
dc.subject Antiretroviral therapy (ART) en_ZA
dc.subject Human immunodeficiency virus (HIV) en_ZA
dc.subject Pregnant women en_ZA
dc.subject Prevention of mother–to–child transmission (PMTCT) en_ZA
dc.subject Major clinical study en_ZA
dc.subject Maternity ward en_ZA
dc.subject Obstetric delivery en_ZA
dc.subject Perceptions en_ZA
dc.subject Prenatal care en_ZA
dc.subject Swaziland en_ZA
dc.subject Antenatal care (ANC) en_ZA
dc.title Factors associated with the lack of antiretroviral therapy initiation among eligible HIV-positive pregnant women in Swaziland en_ZA
dc.type Article en_ZA


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