Etiology of bacterial vaginosis and polymicrobial biofilm formation
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Date
Authors
Jung, Hyun-Sul
Ehlers, Marthie Magdaleen
Lombaard, Hennie
Redelinghuys, Mathys J.
Kock, Marleen M.
Journal Title
Journal ISSN
Volume Title
Publisher
Taylor and Francis
Abstract
Microorganisms in nature rarely exist in a planktonic form, but in the form of biofilms. Biofilms have been identified as the cause of many chronic and persistent infections and have been implicated in the etiology of bacterial vaginosis (BV). Bacterial vaginosis is the most common form of vaginal infection in women of reproductive age. Similar to other biofilm infections, BV biofilms protect the BV-related bacteria against antibiotics and cause recurrent BV. In this review, an overview of BV-related bacteria, conceptual models and the stages involved in the polymicrobial BV biofilm formation will be discussed.
Description
Keywords
Biofilm, Pathogenesis, Gardnerella vaginalis, Bacterial vaginosis (BV), Bacterial vaginosis-associated bacteria (BVAB), Vaginal epithelial cells, Innate immune response, Peroxide-producing lactobacilli, Smplex virus 2 (HSV-2), Genital tract, Volatile fatty acids, Atopobium vaginae, Ureaplasma urealyticum
Sustainable Development Goals
Citation
Jung, H.S., Ehlers, M.M., Lombaard, H., Redelinghuys, M.J. & Kock, M.M. 2017, 'Etiology of bacterial vaginosis and polymicrobial biofilm formation', Critical Reviews in Microbiology, vol. 43, no. 6, pp. 651-667.