The pharmacological management of depression – update 2017

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dc.contributor.author Osuch, Elzbieta
dc.contributor.author Marais, Andre
dc.date.accessioned 2017-08-18T05:23:47Z
dc.date.available 2017-08-18T05:23:47Z
dc.date.issued 2017
dc.description.abstract Depression affects nearly 350 million people worldwide. Local data indicates that approximately 17% of all South Africans will experience at least one episode of depression in their lifetime. Depressive disorders contribute significantly towards overall morbidity and increased risk for suicide. Antidepressant therapy remains one of the cornerstones in the management of depressive disorders. Although the efficacy of antidepressive drugs is continuously subjected to criticism, thousands of controlled clinical trials have shown, and will continue to show, their benefit in the effective treatment of depressive disorders. Since the introduction of antidepressants in the early 1950s, researchers have been searching for an ideal antidepressant able to adequately reduce, preserve and prevent features of depression with the absence of side effects. This article summarizes the currently available antidepressant drugs in South Africa. Discontinued products have been omitted and newly registered agents have been added. This review does not contain reference to any experimental drug, or substances not yet available for local use. en_ZA
dc.description.department Pharmacology en_ZA
dc.description.librarian am2017 en_ZA
dc.description.uri http://www.safpj.co.za/index.php/safpj en_ZA
dc.description.uri http://www.tandfonline.com/oemd en_ZA
dc.identifier.citation Osuch, E. & Marais, A. 2017, 'The pharmacological management of depression – update 2017', South African Family Practice, vol. 59, no. 1, pp. 6-16. en_ZA
dc.identifier.issn 2078-6190 (print)
dc.identifier.issn 2078-6204 (online)
dc.identifier.uri http://hdl.handle.net/2263/61700
dc.language.iso en en_ZA
dc.publisher Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group en_ZA
dc.rights © 2017 The Author(s). Open Access article distributed under the terms of the Creative Commons License [CC BY-NC-ND 4.0]. en_ZA
dc.subject Major depressive disorder (MDD) en_ZA
dc.subject Antidepressant en_ZA
dc.subject Serotonin en_ZA
dc.subject Noradrenaline en_ZA
dc.subject Dopamine en_ZA
dc.title The pharmacological management of depression – update 2017 en_ZA
dc.type Article en_ZA


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