A great deal of work has been conducted on in-tube condensation in horizontal and vertical smooth tubes. The available literature points to mechanisms governing two-phase condensation heat transfer coefficients and pressure drops, which are directly linked to the local flow pattern for both horizontal and inclined configurations. However, the work has been limited to flow pattern observations, heat transfer, pressure drops and void fractions for both horizontal and inclined tubes at high mass fluxes. No work has been conducted on the analysis of the observed flow patterns and the effect of temperature difference between the average wall temperature and average saturation temperature for different inclination angles at mass fluxes of 100 kg/m2.s and below. The purpose of this study is to carry out a qualitative analysis of flow patterns, and show the effect of temperature difference on the heat transfer coefficient for inclination angles from +90° (upward flow) to -90° (downward flow) at mass fluxes below 100 kg/m2.s. An experimental set-up provided the measurements for the two-phase condensation of R-143a in a smooth tube with an inside diameter of 8.38 mm and a length of 1.5 m. The mass fluxes were 25 kg/m2.s to 100 kg/m2.s, the saturation temperature was 40 °C and the mean qualities were 0.1 to 0.9. A high-speed camera was used to visually analyse and determine the flow patterns for both the inlet and the outlet of the test section. Through the results, eight flow patterns were observed: stratified-wavy, stratified, wavy, wavy-churn, intermittent, churn, annular and wavy-annular. The maximum heat transfer was observed for downward flow between inclination angles of -15° and -30°. The Thome-Hajal flow pattern map correctly predicted horizontal flow patterns, but failed to predict most of the inclined flow patterns. Various flow pattern transitions were identified and proposed for all the investigated inclination angles in this study. Finally, the heat transfer coefficient was found to be dependent on quality, mass flux, temperature difference and inclination angle.