dc.contributor.author |
Stoltz, Anton Carel
|
|
dc.contributor.author |
Du Plessis, Andre
|
|
dc.contributor.author |
Andronikou, Savvas
|
|
dc.contributor.author |
Swart, Anelia
|
|
dc.contributor.author |
Scholtz, Leonie
|
|
dc.contributor.author |
Khan, Aneesah
|
|
dc.contributor.author |
Moosa, Aqeela
|
|
dc.date.accessioned |
2017-06-06T07:37:34Z |
|
dc.date.available |
2017-06-06T07:37:34Z |
|
dc.date.issued |
2016-11-11 |
|
dc.description.abstract |
BACKGROUND : Of all areas worldwide, sub-Saharan Africa is worst affected by the HIV and/or
AIDS epidemic. Cardiovascular manifestations are very common and are a powerful
contributor to mortality, but often go undetected. Cardiovascular magnetic resonance (CMR)
is the most reliable method of assessing cardiac function and morphology and, with this in
mind, we initiated a cross-sectional study comparing CMR-determined morphological and
functional parameters in asymptomatic HIV-infected patients who were not yet on treatment
and early in the disease, with HIV-uninfected control patients.
OBJECTIVES : To ascertain whether there were any morphological abnormalities or systolic
functional impairments on CMR in untreated asymptomatic HIV-infected patients, compared
with HIV-uninfected control individuals.
METHODS : The CMR studies were performed using a 1.5-T whole-body clinical magnetic
resonance 16-channel scanner (Achieva, Philips Medical Systems, Best, The Netherlands),
using a cardiac five-element phased-array receiver coil (SENSE coil). Functional assessment
was performed on 36 HIV-infected patients and the findings compared with 35 HIV-uninfected
control patients who were matched for age and sex.
RESULTS : There was no significant difference in systolic function between the HIV-uninfected
and the HIV-infected patients. The left ventricular end diastolic mass (LVEDM) was slightly
higher in the HIV-infected group, but this was statistically insignificant.
CONCLUSION : No significant differences were found regarding the CMR systolic functional
analysis and morphological parameters between the HIV-infected and the healthy volunteers. |
en_ZA |
dc.description.department |
Internal Medicine |
en_ZA |
dc.description.department |
Radiology |
en_ZA |
dc.description.librarian |
am2017 |
en_ZA |
dc.description.uri |
http://www.sajr.org.za/ |
en_ZA |
dc.identifier.citation |
Scholtz L, Du Plessis A, Andronikou S, et al. Systolic function evaluated with cardiovascular magnetic resonance
imaging in HIV-infected patients. S Afr J Rad. 2016;20(2), a1044. http://dx.doi.org/10.4102/sajr.v20i2.1044. |
en_ZA |
dc.identifier.uri |
http://hdl.handle.net/2263/60896 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
AOSIS OpenJournals |
en_ZA |
dc.rights |
© 2016. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. |
en_ZA |
dc.subject |
Patients |
en_ZA |
dc.subject |
Human immunodeficiency virus (HIV) |
en_ZA |
dc.subject |
Cardiovascular magnetic resonance (CMR) |
en_ZA |
dc.subject |
Left ventricular end diastolic mass (LVEDM) |
en_ZA |
dc.title |
Systolic function evaluated with cardiovascular magnetic resonance imaging in HIV-infected patients |
en_ZA |
dc.type |
Article |
en_ZA |