Methicillin-resistant Staphylococcus aureus multiple sites surveillance : a systemic review of the literature

Show simple item record Chipolombwe, John Torok, Mili Estee Mbelle, Nontombi Marylucy Nyasulu, Peter S. 2017-05-31T05:38:12Z 2017-05-31T05:38:12Z 2016-02-12
dc.description.abstract PURPOSE : The objective of this study was to evaluate the optimal number of sampling sites for detection of methicillin-resistant Staphylococcus aureus (MRSA) colonization. METHODS : We performed a Medline search from January 1966 to February 2014 for articles that reported the prevalence of MRSA at different body sites. Studies were characterized by study design, country and period of the study, number of patients and/or isolates of MRSA, specimen type, sites of MRSA isolation, study population sampled, diagnostic testing method, and percentage of the MRSA isolates at each site in relation to the total number of sites. RESULTS : We reviewed 3,211 abstracts and 177 manuscripts, of which 17 met the criteria for analysis (n=52,642 patients). MRSA colonization prevalence varied from 8% to 99% at different body sites. The nasal cavity as a single site had MRSA detection sensitivity of 68% (34%–91%).The throat and nares gave the highest detection rates as single sites. A combination of two swabs improved MRSA detection rates with the best combination being groin/throat (89.6%; 62.5%–100%). A combination of three swab sites improved MRSA detection rate to 94.2% (81%–100%) with the best combination being groin/nose/throat. Certain combinations were associated with low detection rates. MRSA detection rates also varied with different culture methods. CONCLUSION : A combination of three swabs from different body sites resulted in the highest detection rate for MRSA colonization. The use of three swab sites would likely improve the recognition and treatment of MRSA colonization, which may in turn reduce infection and transmission of MRSA to other patients. en_ZA
dc.description.department Medical Microbiology en_ZA
dc.description.librarian am2017 en_ZA
dc.description.uri en_ZA
dc.identifier.citation Chipolombwe, J, Torok, ME, Mbelle, N & Nyasulu, P 2016, 'Methicillin-resistant Staphylococcus aureus multiple sites surveillance : a systemic review of the literature', Infection and Drug Resistance, vol. 9, pp. 35-42. en_ZA
dc.identifier.issn 1178-6973 (online)
dc.identifier.other 10.2147/IDR.S95372
dc.language.iso en en_ZA
dc.publisher Dove Medical Press en_ZA
dc.rights © 2016 Chipolombwe et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( en_ZA
dc.subject Staphylococcus colonization en_ZA
dc.subject Swab sites en_ZA
dc.subject MRSA detection en_ZA
dc.subject Methicillin-resistant Staphylococcus aureus (MRSA) en_ZA
dc.title Methicillin-resistant Staphylococcus aureus multiple sites surveillance : a systemic review of the literature en_ZA
dc.type Article en_ZA

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