Studies on the action of potassium monofluoroacetate (CH₂FCOOK) [Dichapetalum cymosum (Hook) Engl.] toxin on animals

Abstract

1. Considerable variation in susceptibility to potassium mono-fluoroacetate has been found to exist among various species of laboratory animals. 2. The compound is not affected by actively fermenting ruminal flora nor does its presence affect such fermentation. 3. Direct observation on the hearts of rabbits and sheep injected with this compound have proved it to be a heart poison probably affecting the cardiac conducting mechanism thus leading to partial or complete heartblock.