Transvaalin, a cardiac glycoside isolated from Urginea burkei, Bkr. (Transvaal Slangkop)

Show simple item record Louw, P.G.J.
dc.contributor.editor Alexander, R.A.
dc.contributor.editor Clark, R.
dc.contributor.editor Louw, J.G.
dc.contributor.editor De Kock, V.E. 2017-02-06T09:38:43Z 2017-02-06T09:38:43Z 2017 1952
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_ZA
dc.description.abstract (1) A cardiac glycoside, transvaalin, with molecular formula C₃₆H₅₂O₁₃, was isolated from Urginea burkei Bkr. (2) Transvaalin has the typical raticidal properties of scilliroside when dosed per os or injected intraperitoneally. The m.l.d. for rats, dosed per os, was 40 mg./Kg. (3) Hydrolysis of transvaalin yielded scillaridin A, C₂₄H₃₀O₃, and scillabiose from which it appears that transvaalin must either be isomeric with scillaren A or a very stable complex of scillaren A and a rat-poison e.g. scilliroside. (4) Fractionation of transvaalin with chloroform-butanol yielded no scilliroside or other rat-poison, while the activity of transvaalin remained unchanged towards rats and frogs, contradicting the possibility that it is a complex of scillaren A and a rat-poison. (5) The isolation (in small yield) of an amorphous water-soluble poisonous principle from U. burkei. is reported. en_ZA
dc.identifier.citation Louw, PGJ 1952, 'Transvaalin, a cardiac glycoside isolated from Urginea burkei, Bkr. (Transvaal Slangkop)’, Onderstepoort Journal of Veterinary Research, vol. 25, no. 4, pp. 123-133. en_ZA
dc.identifier.issn 0330-2465
dc.language.iso en en_ZA
dc.publisher Published by The Government Printer, Pretoria en_ZA
dc.rights © 1952 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2017 University of Pretoria. Dept. of Library Services (digital). en_ZA
dc.subject Veterinary medicine en_ZA
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title Transvaalin, a cardiac glycoside isolated from Urginea burkei, Bkr. (Transvaal Slangkop) en_ZA
dc.type Article en_ZA

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