Strain 19 Brucella vaccine: V. Mass production in the Brucella Vortex Aerated Culture apparatus

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Authors

Van Drimmelen, G.C.

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Published by The Government Printer, Pretoria

Abstract

The vaccine organism Brucella abortus strain 19 has been cultured in bulk in 72 litres of liquid medium aerated in a vortex system in a stainless steel culture vessel of 250 litre capacity. The lay-out and operation of the apparatus are described and results of a series of batches produced are given. The differences between various production methods are briefly presented.

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The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.

Keywords

Veterinary medicine

Sustainable Development Goals

Citation

Van Drimmelen, GC 1958, 'Strain 19 brucella vaccine: V. Mass production in the Brucella Vortex Aerated Culture apparatus', Onderstepoort Journal of Veterinary Research, vol. 27, no. 4, pp. 539-547.