Abstract:
The vaccine organism Brucella abortus strain 19
has
been
cultured
in
bulk
in
72
litres
of
liquid
medium
aerated
in
a
vortex
system
in
a
stainless
steel
culture
vessel
of
250
litre
capacity.
The
lay-out
and
operation
of
the
apparatus
are
described
and
results
of
a
series
of
batches
produced
are
given.
The
differences
between
various
production
methods
are
briefly
presented.
