Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya

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dc.contributor.author Toye, Philip
dc.contributor.author Handel, Ian
dc.contributor.author Gray, Julia
dc.contributor.author Kiara, Henry
dc.contributor.author Thumbi, Samuel
dc.contributor.author Jennings, Amy
dc.contributor.author Conradie Van Wyk, Ilana
dc.contributor.author Ndila, Mary
dc.contributor.author Hanotte, Olivier
dc.contributor.author Coetzer, Jacobus A.W.
dc.contributor.author Woolhouse, Mark
dc.contributor.author Bronsvoort, Mark
dc.date.accessioned 2016-12-06T06:22:38Z
dc.date.available 2016-12-06T06:22:38Z
dc.date.issued 2013-09
dc.description.abstract The passive transfer of antibodies from dams to offspring via colostrum is believed to play an important role in protecting neonatal mammals from infectious disease. The study presented here investigates the uptake of colostrum by 548 calves in western Kenya maintained under smallholder farming, an important agricultural system in eastern Africa. Serum samples collected from the calves and dams at recruitment (within the first week of life) were analysed for the presence of antibodies to four tick-borne haemoparasites: Anaplasma marginale, Babesia bigemina, Theileria mutans and Theileria parva. The analysis showed that at least 89.33% of dams were seropositive for at least one of the parasites, and that 93.08% of calves for which unequivocal results were available showed evidence of having received colostrum. The maternal antibody was detected up until 21 weeks of age in the calves. Surprisingly, there was no discernible difference in mortality or growth rate between calves that had taken colostrum and those that had not. The results are also important for interpretation of serosurveys of young calves following natural infection or vaccination. en_ZA
dc.description.department Veterinary Tropical Diseases en_ZA
dc.description.librarian hb2016 en_ZA
dc.description.sponsorship The Wellcome Trust (grant No. 079445) . Open Access funded by Wellcome Trust. en_ZA
dc.description.uri http://www.elsevier.com/locate/vetimm en_ZA
dc.identifier.citation Toye, P, Handel, I, Gray, J, Kiara, H, Thumbi, S, Jennings, A, Van Wyk, IC, Ndila, M, Hanotte, O, Coetzer, K, Woolhouse, M & Bronsvoort, M 2013, 'Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya', Veterinary Immunology and Immunopathology, vol. 155, no. 1-2, pp. 129-134. en_ZA
dc.identifier.issn 0165-2427 (print)
dc.identifier.issn 1873-2534 (online)
dc.identifier.other 10.1016/j.vetimm.2013.06.003
dc.identifier.uri http://hdl.handle.net/2263/58355
dc.language.iso en en_ZA
dc.publisher Elsevier en_ZA
dc.rights © 2013 The Authors. Published by Elsevier B.V. Open access under Creative Commons Attribution 3.0 Unported (CC BY 3.0) license. en_ZA
dc.subject Colostrum en_ZA
dc.subject Maternal antibodies en_ZA
dc.subject Calves en_ZA
dc.subject Smallholder systems en_ZA
dc.subject Haemoparasites en_ZA
dc.title Maternal antibody uptake, duration and influence on survival and growth rate in a cohort of indigenous calves in a smallholder farming system in western Kenya en_ZA
dc.type Article en_ZA


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