Human immunodeficiency virus (HIV)-infected patients accept finger stick blood collection for point-of-care CD4 testing

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dc.contributor.author Daneau, Geraldine
dc.contributor.author Gous, Natasha
dc.contributor.author Scott, Lesley
dc.contributor.author Potgieter, Joachim
dc.contributor.author Kestens, Luc
dc.contributor.author Stevens, Wendy
dc.date.accessioned 2016-11-04T05:31:35Z
dc.date.available 2016-11-04T05:31:35Z
dc.date.issued 2016-08-24
dc.description S1 File. Questionnaire for group 1 in South Africa. Patients with single finger stick. (PDF) en_ZA
dc.description S2 File. Questionnaire for group 2 in South Africa. Patients with multiple finger stick. (PDF) en_ZA
dc.description S3 File. First questionnaire in Antwerp (English). For preference immediately after finger stick. (PDF) en_ZA
dc.description S4 File. First questionnaire in Antwerp (Dutch). For preference immediately after finger stick. (PDF) en_ZA
dc.description S5 File. First questionnaire in Antwerp (French). For preference immediately after finger stick. (PDF) en_ZA
dc.description S6 File. Second questionnaire in Antwerp (English). For preference two days after finger stick. (PDF) en_ZA
dc.description S7 File. Second questionnaire in Antwerp (Dutch). For preference two days after finger stick. (PDF) en_ZA
dc.description S8 File. Second questionnaire in Antwerp (French). For preference two days after finger stick. (PDF) en_ZA
dc.description.abstract INTRODUCTION HIV-infected patients require antiretroviral treatment for life. To improve access to care, CD4 enumeration and viral load tests have been redesigned to be used as point-of-care techniques using finger-stick blood. Accurate CD4 counting in capillary blood requires a free flowing blood drop that is achieved by blade incision. The aim of this study was to assess the attitude of the patients toward blade-based finger-stick blood donation. METHODS Four hundred and ninety-nine patients were included (299 patients from South Africa and 200 from Belgium). They completed a questionnaire to express their preference for finger stick or venipuncture, after undergoing both. The South African patient cohort was divided in two groups, receiving either single or multiple finger stick for CD4 and other HIV-related tests. The Belgian patients received a single finger stick for CD4 testing, and were asked to respond directly and again after two days. RESULTS The majority of the patients preferred the finger stick to the venipuncture. The perceived pain using the blade was superior to a small needle, but similar to a large needle. They preferred up to three finger sticks over one venipuncture. Up to 30% of the patients changed their mind over two days. The main reason for choosing a finger stick was continued bleeding after venipuncture. The most cited objection to finger stick was pain/soreness. CONCLUSION Patient perceptions support the implementation of donating capillary blood with bladebased finger stick during CD4 point-of-care testing. en_ZA
dc.description.department Haematology en_ZA
dc.description.librarian am2016 en_ZA
dc.description.sponsorship The study in South Africa was funded by Grand Challenges Canada [Grant number 0007-02-01-01, url http://www.grandchallenges.ca] en_ZA
dc.description.uri http://www.plosone.org en_ZA
dc.description.uri http://www.grandchallenges.ca en_ZA
dc.identifier.citation Daneau G, Gous N, Scott L, Potgieter J, Kestens L, Stevens W (2016) Human Immunodeficiency Virus (HIV)-Infected Patients Accept Finger Stick Blood Collection for Point-Of- Care CD4 Testing. PLoS ONE 11(8): e0161891. DOI: 10.1371/journal.pone.0161891. en_ZA
dc.identifier.issn 1932-6203
dc.identifier.other 10.1371/journal.pone.0161891
dc.identifier.uri http://hdl.handle.net/2263/57654
dc.language.iso en en_ZA
dc.publisher Public Library of Science en_ZA
dc.rights © 2016 Daneau et al. This is an open access article distributed under the terms of the Creative Commons Attribution License. en_ZA
dc.subject CD4 en_ZA
dc.subject Human immunodeficiency virus (HIV) en_ZA
dc.subject HIV-infected patients en_ZA
dc.subject Antiretroviral treatment (ART) en_ZA
dc.subject Viral load tests en_ZA
dc.subject Finger-stick blood. en_ZA
dc.subject.other Health sciences articles SDG-03
dc.subject.other SDG-03: Good health and well-being
dc.subject.other Health sciences articles SDG-09
dc.subject.other SDG-09: Industry, innovation and infrastructure
dc.subject.other Health sciences articles SDG-10
dc.subject.other SDG-10: Reduced inequalities
dc.title Human immunodeficiency virus (HIV)-infected patients accept finger stick blood collection for point-of-care CD4 testing en_ZA
dc.type Article en_ZA


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