In the past 10 years or so, many alternatives to warfarin have been developed the first being the novel oral anticoagulants (NOAC)
or better referred to as direct oral anticoagulants (DOAC) or target-specific oral anticoagulants (TSOAC). These drugs have some
definite advantages and disadvantages that should be clear to physicians before prescribing any of them for patients. Many clinical
trials have provided definitive information about the efficacy and safety of DOACs, yet many physicians remain sceptical about
prescribing these drugs due to lack of answers to real world questions. The concerns are directed towards appropriate patient
selection (the choice should be made according to age, renal function, compliance, cost, clinical condition, intake of other drugs),
the mechanism of switching between agents, how these drugs affect routine laboratory tests and when monitoring is needed.
Knowledge of other drugs that interact with the DOAC and management of severe bleeding will be reviewed and recommendations
will be given to all of these concerns.
The use of herbal preparations for staunching blood flow and reducing the risk of vascular thrombosis is common worldwide. In this study, aqueous and methanolic extracts of plants used to treat blood-associated complaints ...
CONTEXT: Herbal remedies are used to treat a large variety of diseases, including blood-related disorders. However, a number of herbal preparations have been reported to cause variations in clotting time, this is mainly ...