Deaths associated with respiratory syncytial and influenza viruses among persons greater or equal to 5 years of age in HIV- prevalent area, South Africa, 1998 - 2009

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dc.contributor.author Tempia, Stefano
dc.contributor.author Walaza, Sibongile
dc.contributor.author Vibound, Cecile
dc.contributor.author Cohen, Adam L.
dc.contributor.author Madhi, Shabir A.
dc.contributor.author Venter, Marietjie
dc.contributor.author Von Mollendorf, Claire
dc.contributor.author Moyes, Jocelyn
dc.contributor.author McAnerney, Johanna M.
dc.contributor.author Cohen, Cheryl
dc.date.accessioned 2016-08-30T12:54:11Z
dc.date.available 2016-08-30T12:54:11Z
dc.date.issued 2015-04
dc.description Data from this study were presented in part at the Options for the Control of Influenza Conference VIII; 2013 Sep 5–10; Cape Town, South Africa. en_ZA
dc.description.abstract We estimated deaths attributable to influenza and respiratory syncytial virus (RSV) among persons >5 years of age in South Africa during 1998–2009 by applying regression models to monthly deaths and laboratory surveillance data. Rates were expressed per 100,000 person-years. The mean annual number of seasonal influenza–associated deaths was 9,093 (rate 21.6). Persons >65 years of age and HIV-positive persons accounted for 50% (n = 4,552) and 28% (n = 2,564) of overall seasonal influenza-associated deaths, respectively. In 2009, we estimated 4,113 (rate 9.2) influenza A(H1N1)pdm09–associated deaths. The mean of annual RSV-associated deaths during the study period was 511 (rate 1.2); no RSV-associated deaths were estimated in persons >45 years of age. Our findings support the recommendation for influenza vaccination of older persons and HIV-positive persons. Surveillance for RSV should be strengthened to clarify the public health implications and severity of illness associated with RSV infection in South Africa. en_ZA
dc.description.department Medical Virology en_ZA
dc.description.librarian am2016 en_ZA
dc.description.uri www.cdc.gov/eid en_ZA
dc.identifier.citation Tempia, S, Walaza, S, Viboud, C, Cohen AL, Madhi, S, Venter, M, Von Mollendorf, C, Moyes, J, McAnerney, J & Cohen, C 2016, 'Deaths associated with respiratory syncytial and influenza viruses among persons greater or equal to 5 years of age in HIV- prevalent area, South Africa, 1998 - 2009', Emerging Infectious Diseases, vol. 21, no. 4, pp. 600-608. en_ZA
dc.identifier.issn 1080-6040 (print)
dc.identifier.issn 1080-6059 (online)
dc.identifier.other 10.3201/eid2104.141033
dc.identifier.uri http://hdl.handle.net/2263/56492
dc.language.iso en en_ZA
dc.publisher Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention en_ZA
dc.rights Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention en_ZA
dc.subject Deaths en_ZA
dc.subject HIV-positive persons en_ZA
dc.subject Respiratory syncytial virus (RSV) en_ZA
dc.subject South Africa (SA) en_ZA
dc.subject Human immunodeficiency virus (HIV) en_ZA
dc.title Deaths associated with respiratory syncytial and influenza viruses among persons greater or equal to 5 years of age in HIV- prevalent area, South Africa, 1998 - 2009 en_ZA
dc.type Article en_ZA


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