The effect of immunosuppression on the development of immunity to fowl typhoid

Show simple item record Brett, O.L. Fuls, W.J.P. Cameron, Colin McKenzie
dc.contributor.editor Verster, Anna J.M.
dc.contributor.editor Walker, Jane B.
dc.contributor.editor Bigalke, R.D.
dc.contributor.editor Cameron, Colin McKenzie
dc.contributor.other De Kock, V.E. 2016-07-07T06:40:42Z 2016-07-07T06:40:42Z 2016 1974
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_ZA
dc.description.abstract Chickens which were given cyclophosphamide during the first three to five days of life showed a marked depression in their humoral antibody response to sheep erythrocytes and Brucella antigen. Their ability to develop tuberculin sensitivity and their immune response to live Salmonella gallinarum vaccine was, however, unimpaired. The administration of methylprednisoline acetate, hydrocortisone acetate, azathioprim and 6-mercaptopurine to either six or 10 to 12-week-old chickens neither selectively depressed the humoral or cellular immune response nor affected the immune response to live S. gallinarum vaccine. Similarly, the immune response could not be depressed by thymectomy or antilymphocyte globulin. These results indicate that immunity to S. gallinarum after administration of a live avirulent vaccine is not dependent on a humoral immune mechanism but probably primarily on cellular immunity, although this could not be proven. en_ZA
dc.identifier.citation Cameron, CM, Brett, OL & Fuls, WJP 1974, 'The effect of immunosuppression on the development of immunity to fowl typhoid’, Onderstepoort Journal of Veterinary Research, vol. 41, no. 1, pp. 15-21. en_ZA
dc.identifier.issn 0330-2465
dc.language.iso en en_ZA
dc.publisher Pretoria : The Government Printer en_ZA
dc.rights ©1974 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original) ©2016 University of Pretoria. Department of Library Services (digital) en_ZA
dc.subject Veterinary medicine en_ZA
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title The effect of immunosuppression on the development of immunity to fowl typhoid en_ZA
dc.type Article en_ZA

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