The indirect fluorescent antibody test was employed to determine levels of serum antibodies in cattle and sheep infested with Schistosoma mattheei. Using smears of schistosome cercariae as antigen, a high degree of specificity and sensitivity was obtained. High titres were obtained in sera from all the animals infested with schistosomiasis, while those from animals infested with various other helminths gave negative results. The antigen-antibody complex appeared to be localised in the cuticle of the cercaria.
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