Transplantation of cultured jaagsiekte (sheep pulmonary adenomatosis) cells into athymic nude mice

Show simple item record Du Plessis, J.L. Verwoerd, Daniel Wynand Meyer-Scharrer, Elizabeth
dc.contributor.editor Bigalke, R.D.
dc.contributor.editor Cameron, Colin McKenzie
dc.contributor.editor Gilchrist, Frances M.C.
dc.contributor.editor Morren, A.J.
dc.contributor.editor Verster, Anna J.M.
dc.contributor.editor Verwoerd, Daniel Wynand
dc.contributor.editor Walker, Jane B.
dc.contributor.other De Kock, V.E. 2016-07-06T12:20:21Z 2016-07-06T12:20:21Z 2016 1977
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_ZA
dc.description.abstract Epithelial cells of the 15 .4 line, which were originally established from the adenomatous lung of a jaagsiekte case and which had been cultured in vitro for 22 generations, were injected subcutaneously into athymic nude mice. A slow-growing tumour which soon became cystic was established in each case. The cysts rapidly increased in size as a result of the accumulation of a slightly turbid secretion containing aggregates of tumour cells which rapidly refilled the cysts after the fluid had been withdrawn. Cultures were readily re-established from these cells and a chromosomal analysis proved that the tumour consisted of sheep cells. An epithelial cell lining, very similar to that found in the adenomatous lung alveoli of typical jaagsiekte, could be demonstrated histologically. en_ZA
dc.identifier.citation Verwoerd, DW, Meyer-Sharrer, E & Du Plessis, JL 1977, 'Transplantation of cultured jaagsiekte (sheep pulmonary adenomatosis) cells into athymic nude mice’, Onderstepoort Journal of Veterinary Research, vol. 44, no. 4, pp. 271-273. en_ZA
dc.identifier.issn 0330-2465
dc.language.iso en en_ZA
dc.publisher The Government Printer, Pretoria en_ZA
dc.rights © 1977 ARC – Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2016 University of Pretoria. Department of Library Services (digital). en_ZA
dc.subject Veterinary Medicine en_ZA
dc.subject.lcsh Veterinary Medicine -- South Africa
dc.title Transplantation of cultured jaagsiekte (sheep pulmonary adenomatosis) cells into athymic nude mice en_ZA
dc.type Article en_ZA

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