Production and application of a live Salmonella gallinarum vaccine

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Authors

Cameron, Colin McKenzie
Buys, S.B.

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Published by The Government Printer, Pretoria

Abstract

The production and application of a freeze-dried Salmonella gallinarum vaccine are described in this report. The vaccine is stable when kept at 4 °C and a single injection elicits a good immunity for 2 months, though its effect gradually diminishes. Immunity is neither enhanced nor depressed by repeated injections of the live vaccine, and no interference effect was observed in experimentally infected chickens. Furazolidone therapy jeopardizes the immunogenicity of a live vaccine, but its effect can be countered by the administration of either an inactivated or a live vaccine when medication is commenced and this is followed by the application of live vaccine 6 days after cessation of medication.

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This article has been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-Format.

Keywords

Veterinary medicine

Sustainable Development Goals

Citation

Cameron, CM & Buys, SB 1979, 'Production and application of a live Salmonella gallinarum vaccine’, Onderstepoort Journal of Veterinary Research, vol. 46, no. 4, pp. 185-189.