Factors affecting the bluetongue virus neutralizing antibody response and the reaction between virus and antibody
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Authors
Van der Walt, N.T.
Journal Title
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Published by The Government Printer, Pretoria
Abstract
A study was made of different aspects of the bluetongue virus neutralizing antibody response and the reaction between the virus and antibody. Optimum neutralization was obtained in a 2 mM Tris-HCl buffer, pH 9,0, at a temperature of 4 °C. The reaction of virus and antibody could be demonstrated by electron microscopy in the formation of clumps which were shown to be serotype specific. It was found that both IgM and IgG antibodies can neutralize the virus, but that IgM reached its maximum level sooner after infection than IgG.
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Keywords
Veterinary medicine
Sustainable Development Goals
Citation
Van der Walt, NT 1979, 'Factors affecting the bluetongue virus neutralizing antibody response and the reaction between virus and antibody’, Onderstepoort Journal of Veterinary Research, vol. 46, no. 2, pp. 111-116.