Factors affecting the bluetongue virus neutralizing antibody response and the reaction between virus and antibody

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Van der Walt, N.T.

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Published by The Government Printer, Pretoria

Abstract

A study was made of different aspects of the bluetongue virus neutralizing antibody response and the reaction between the virus and antibody. Optimum neutralization was obtained in a 2 mM Tris-HCl buffer, pH 9,0, at a temperature of 4 °C. The reaction of virus and antibody could be demonstrated by electron microscopy in the formation of clumps which were shown to be serotype specific. It was found that both IgM and IgG antibodies can neutralize the virus, but that IgM reached its maximum level sooner after infection than IgG.

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This article has been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-Format.

Keywords

Veterinary medicine

Sustainable Development Goals

Citation

Van der Walt, NT 1979, 'Factors affecting the bluetongue virus neutralizing antibody response and the reaction between virus and antibody’, Onderstepoort Journal of Veterinary Research, vol. 46, no. 2, pp. 111-116.