dc.contributor.author |
Coetzer, Jacobus A.W.
|
|
dc.contributor.author |
Barnard, B.J.H.
|
|
dc.contributor.editor |
Bigalke, R.D. |
|
dc.contributor.editor |
Cameron, Colin McKenzie |
|
dc.contributor.editor |
Gilchrist, Frances M.C. |
|
dc.contributor.editor |
Morren, A.J. |
|
dc.contributor.editor |
Verster, Anna J.M. |
|
dc.contributor.editor |
Verwoerd, Daniel Wynand |
|
dc.contributor.editor |
Walker, Jane B. |
|
dc.contributor.other |
De Kock, V.E. |
|
dc.date.accessioned |
2016-07-06T11:56:33Z |
|
dc.date.available |
2016-07-06T11:56:33Z |
|
dc.date.created |
2016 |
|
dc.date.issued |
1977 |
|
dc.description |
The articles have been scanned in colour with a HP Scanjet 5590; 300dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. |
en_ZA |
dc.description.abstract |
During the 1974/75 lambing season numerous reports were received from various parts of the
Republic of South Africa and South West Africa of severe abdominal distension in ewes after
vaccination with the attenuated Rift Valley fever and/or attenuated Wesselsbron disease vaccine. The ewes were vaccinated at different stages of gestation in spite of recommendations to the contrary, the syndrome being especially obvious in ewes immunized with one or both of these vaccines during the first trimester of pregnancy. In some of the flocks hydrops amnii was recorded in as many as 15% of the ewes. Many of the ewes so affected showed a prolonged gestation of up to 6-7 months and, towards the end of gestation, were unable to rise or walk. They eventually died of ketosis, hypostatic pneumonia and complications due to dystocia. The foetuses examined were malformed and larger than normal with a mass of 3,6-6,7 kg. They usually showed arthrogryposis, brachygnathy inferior, hydranencephaly, hypoplasia or segmental aplasia of the spinal cord and neurogenic muscular atrophy. The amnion contained 8,0-18,0 l of amniotic fluid, the endometrium was oedematous, and cystic tube-like dilatations, 1-10 mm in diameter, filled with a clear fluid, were scattered in the endometrium. No definite conclusions as to the aetiology of the syndrome could be drawn from serological tests performed on the ewes, lambs or foetuses. Preliminary experimental work confirmed previous observations that the attenuated Wesselsbron disease vaccine virus is responsible for this syndrome and that the wild-type virus is also implicated. In addition, the attenuated Rift Valley fever vaccine virus was found to the responsible for arthrogryposis and hydranencephaly without hydrops amnii and for micrencephaly and arthrogryposis associated with hydrops amnii in the ewe. |
en_ZA |
dc.identifier.citation |
Coetzer, JAW & Barnard, BJH 1977, 'Hydrops amnii in sheep associated with hydranencephaly and arthrogryposis with Wesselsbron disease and Rift Valley fever viruses as aetiological agents.’, The Onderstepoort Journal of Veterinary Research, vol. 44, no. 2, pp. 119-126. |
en_ZA |
dc.identifier.issn |
0330-2465 |
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dc.identifier.uri |
http://hdl.handle.net/2263/53772 |
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dc.language.iso |
en |
en_ZA |
dc.publisher |
Pretoria : The Government Printer |
en_ZA |
dc.rights |
© 1977 ARC – Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original).
© 2016 University of Pretoria. Department of Library Services (digital). |
en_ZA |
dc.subject |
Sheep -- Diseases |
en_ZA |
dc.subject |
Wesselsbron disease |
en_ZA |
dc.subject |
Rift Valley fever |
en_ZA |
dc.subject.lcsh |
Veterinary medicine -- South Africa |
|
dc.title |
Hydrops amnii in sheep associated with hydranencephaly and arthrogryposis with Wesselsbron disease and Rift Valley fever viruses as aetiological agents |
en_ZA |
dc.type |
Article |
en_ZA |