The antibody response of cattle to Clostridium botulinum types C and D toxoids

Show simple item record Jansen, B.C. Knoetze, P.C. Visser, F.
dc.contributor.editor Bigalke, R.D.
dc.contributor.editor Cameron, Colin McKenzie
dc.contributor.editor Gilchrist, Frances M.C.
dc.contributor.editor Morren, A.J.
dc.contributor.editor Verster, Anna J.M.
dc.contributor.editor Verwoerd, Daniel Wynand
dc.contributor.editor Walker, Jane B.
dc.contributor.other De Kock, V.E. 2016-07-06T11:47:04Z 2016-07-06T11:47:04Z 2016 1976
dc.description The articles have been scanned in colour with a HP scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to final presentyation PDF-Format. en_ZA
dc.description.abstract The resistance of cattle with varying serum-antitoxin titres was determined by per os challenge. The results proved that a solid immunity can be produced against C. botulinum toxins C₁ and D. The immune response of cattle to various quantities of C. botulinum C₁ and D toxoids, aluminum phosphate adsorbed and in water-in-oil emulsion was investigated. The response to antigen in watering oil emulsion was far superior to the other when they were used for primary and secondary stimuli. When cattle had been given a solid basic immunity with 2 injections of antigen in water-in-oil emulsion, essentially the same booster effect was obtained with antigen in water-in-oil emulsion and in aqueous solution. Only some of the animals injected intramuscularly with antigens in water-in-oil emulsion developed local lesions. These lesions were not large and their histological picture indicated a noticeable decline in severity within 20 weeks. A case is thus made out for the use of C. botulinum C₁ and D toxoids in water-in-oil emulsion for the primary and secondary stimuli and an aqueous solution of these antigens for any booster stimulus as an improved method of protecting cattle against botulism. en_ZA
dc.identifier.citation Jansen, BC, Knoetze, PC & Visser, F 1976, 'The antibody response of cattle to Clostridium botulinum types C and D toxoids’, Onderstepoort Journal of Veterinary Research, vol. 43, no. 4, pp. 165-73. en_ZA
dc.identifier.issn 0330-2465
dc.language.iso en en_ZA
dc.publisher Pretoria : The Government Printer en_ZA
dc.rights ©1976 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©2016 University of Pretoria. Department of Library Services (digital). en_ZA
dc.subject Veterinary medicine en_ZA
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title The antibody response of cattle to Clostridium botulinum types C and D toxoids en_ZA
dc.type Article en_ZA

Files in this item

This item appears in the following Collection(s)

Show simple item record