dc.contributor.author |
Malherbe, W.D.
|
|
dc.contributor.author |
Kellerman, T.S.
|
|
dc.contributor.author |
Kriek, N.P.J.
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|
dc.contributor.author |
Haupt, W.H.
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|
dc.contributor.editor |
Bigalke, R.D. |
|
dc.contributor.editor |
Cameron, Colin McKenzie |
|
dc.contributor.editor |
Gilchrist, Frances M.C. |
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dc.contributor.editor |
Morren, A.J. |
|
dc.contributor.editor |
Verster, Anna J.M. |
|
dc.contributor.editor |
Verwoerd, Daniel Wynand |
|
dc.contributor.editor |
Walker, Jane B. |
|
dc.contributor.other |
De Kock, V.E. |
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dc.date.accessioned |
2016-07-06T10:17:01Z |
|
dc.date.available |
2016-07-06T10:17:01Z |
|
dc.date.created |
2016 |
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dc.date.issued |
1977 |
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dc.description |
The articles have been scanned in colour with a HP Scanjet 5590; 300dpi.
Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. |
en_ZA |
dc.description.abstract |
A brief survey of the literature on gamma-glutamyl transpeptidase (ƴ-GT) activity is included in this study. The levels of activity in the serum of normal Merino sheep (13, 6- 32, 4 mI.U./ml) were ascertained as a preliminary to following the activity through the entire course of experimentally induced ovine lupinosis, a hepatotoxicosis caused by Phomopsis leptostromiformis (Kühn) Bubák. The response of the serum level of ƴ-GT activity to the course of the disease was compared with that of glutamate oxaloacetic transaminase (GOT) and 2 liver function tests for the purpose of assessing its potential application in the study of this mycotoxicosis. Because the levels of activity of ƴ-GT were more valuable for the early diagnosis of low grade acute intoxication and the detection of chronic liver involvement while those of GOT gave better information on the development of severe acute hepato-cellular damage, these 2 enzymes, considered together, were found to give the best information on the course of the toxicosis. The changes in ƴ-GT activity during various stages of intoxication were also related to the histopathological lesions in the liver. |
en_ZA |
dc.identifier.citation |
Malherbe WD, Kellerman, TS, Kriek, NPJ & Haupt WH 1977, 'Gamma-glutamyl transpeptidase activity in sheep serum : normal values and an evaluation of its potential for detecting liver involvement in experimental lupinosis.' Onderstepoort Journal of Veterinary Research, vol. 44, no. 1, pp. 29-39. |
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dc.identifier.issn |
0330-2465 |
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dc.identifier.uri |
http://hdl.handle.net/2263/53700 |
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dc.language.iso |
en |
en_ZA |
dc.publisher |
Pretoria : The Government Printer |
en_ZA |
dc.rights |
© 1977 ARC – Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original).
© 2016 University of Pretoria. Department of Library Services (digital). |
en_ZA |
dc.subject |
Sheep |
en_ZA |
dc.subject.lcsh |
Veterinary medicine -- South Africa |
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dc.title |
Gamma-glutamyl transpeptidase activity in sheep serum : normal values and an evaluation of its potential for detecting liver involvement in experimental lupinosis |
en_ZA |
dc.type |
Article |
en_ZA |